Results 121 to 130 of about 2,315,831 (319)

Persistent phosphorylation parallels long-term desensitization of cerebellar purkinje cell AMPA-type glutamate receptors. [PDF]

, 1997
Kazu Nakazawa, Sumiko Mikawa, M. Ito
openalex   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source

Does It Matter What Keeps You Awake? Effects of Two Different Sleep Deprivation Methods on Object‐Location Memory and Hippocampal c‐Fos Expression in Mice

Journal of Sleep Research, EarlyView.
ABSTRACT In sleep research, various sleep deprivation methods have been used to examine the effects of sleep loss on memory. However, studies often overlook the distinct impacts each method may have on activity in specific neuronal circuits and memory storage.
Adithya Sarma, Mirthe Ronde, Soraya Smit, Peter Meerlo, Robbert Havekes   +4 more
wiley   +1 more source

Alteration in AMPA receptor subunit expression and receptor binding among patients with addictive disorders: A systematic review of human postmortem studies

Neuropsychopharmacology Reports, 2019
Background and Objectives Altered trafficking of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptors has been reported in postmortem studies and suggested the involvement of AMPA receptors in the pathophysiology underpinning addictive ...
Fumihiko Ueno, Takefumi Suzuki, Shinichiro Nakajima, Sachio Matsushita, Masaru Mimura, Tomoyuki Miyazaki, Takuya Takahashi, Hiroyuki Uchida   +7 more
doaj   +1 more source

Linking autism risk genes to morphological and pharmaceutical screening by high‐content imaging: Future directions and opinion

Psychiatry and Clinical Neurosciences, EarlyView.
Next‐generation sequencing has identified risk genes with large effect sizes for autism spectrum disorders (ASD). Although functional analysis of individual risk genes has progressed, the overall picture of ASD pathogenesis is unclear. Therefore, there is a need for morphological profiling of variants in these genes to fully comprehend their ...
Reza K. Arta, Yuichiro Watanabe, Jun Egawa, Vance P. Lemmon, Toshiyuki Someya   +4 more
wiley   +1 more source

NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus [PDF]

, 1998
Hey‐Kyoung Lee, Kimihiko Kameyama, Richard L. Huganir, Mark F. Bear   +3 more
openalex   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Novel Anchorage of GluR2/3 to the Postsynaptic Density by the AMPA Receptor–Binding Protein ABP [PDF]

, 1998
Shalini Srivastava, Pavel Osten, Ferdinand S. Vilim, Latika Khatri, Gareth J. Inman, Bradley A. States, Christopher Daly, Sunita deSouza, Ruben Abagyan, J.G. Valtschanoff, Richard J. Weinberg, Edward B. Ziff   +11 more
openalex   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Kv4 channels improve the temporal processing of auditory neurons in the cochlear nucleus

The Journal of Physiology, EarlyView.
Abstract figure legend Kv4 channel improves temporal precision of auditory nerve‐evoked spikes in cochlear nucleus bushy neurons. Bushy neurons are specialized cells in processing information about temporal fine structure of sound critical for auditory tasks.
Chuangeng Zhang, Meijian Wang, Tingting Zhang, Ruili Xie   +3 more
wiley   +1 more source