Results 191 to 200 of about 53,245 (286)

AMPA receptors get 'pickled' [PDF]

open access: yesNature, 2009
Alexander C. Jackson, Roger A. Nicoll
openaire   +1 more source

Genetic Reduction of the Translational Repressors FMRP and 4E‐BP2 Preserves Memory in Mouse Models of Alzheimer's Disease

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Genetic reduction of the translational repressors FMRP or 4E‐BP2 prevents amyloid‐β oligomer–induced suppression of hippocampal protein synthesis and memory loss in mice. Targeting translational control preserves cognitive function in Alzheimer's models, revealing mRNA translation as a promising therapeutic axis for memory preservation.
Felipe C. Ribeiro   +11 more
wiley   +1 more source

Quantitative DNA-PAINT imaging of AMPA receptors in live neurons. [PDF]

open access: yesCell Rep Methods, 2023
Youn Y   +6 more
europepmc   +1 more source

Calcium-Permeable AMPA Receptors Provide a Common Mechanism for LTP in Glutamatergic Synapses of Distinct Hippocampal Interneuron Types [PDF]

open access: bronze, 2012
András Szabó   +5 more
openalex   +1 more source

Linking Age Changes in Human Cortical Microcircuits to Impaired Brain Function and EEG Biomarkers

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
We integrated human data of aging‐related reductions in inhibition, NMDA function, and dendritic spines into detailed models of cortical microcircuits. Simulations showed that the cellular aging mechanisms accounted for many of the age‐related changes seen in human EEG and could be estimated accurately using machine learning from their EEG biomarkers ...
Alexandre Guet‐McCreight   +3 more
wiley   +1 more source

AMPA Receptors in Synaptic Plasticity, Memory Function, and Brain Diseases. [PDF]

open access: yesCell Mol Neurobiol
de León-López CAM   +2 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

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