Results 231 to 240 of about 2,301,971 (322)

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

Amyloid-β-Driven Synaptic Deficits Are Mediated by Synaptic Removal of GluA3-Containing AMPA Receptors. [PDF]

J Neurosci
Reinders NR, van der Spek SJF, Klaassen RV, Koymans KJ, MacGillavry HD, Smit AB, Kessels HW.   +6 more
europepmc   +1 more source

Editorial: Regulation of AMPA Receptors, From the Genetic to the Functional Level. [PDF]

Front Synaptic Neurosci, 2022
Ouro A, Wong TP, Jiménez-Sánchez L.
europepmc   +1 more source

Neuroprotective Effect of YM9OK, an AMPA-Receptor Antagonist,against Delayed Neuronal Death Induced by Transient Global Cerebral Ischemia in Gerbils and Rats.

, 1997
Sachiko Kawasaki‐Yatsugi, Shin‐ichi Yatsugi, Kazuo Koshiya, Masao Shimizu-Sasamata   +3 more
openalex   +1 more source

Activation of Synaptic NMDA Receptors Induces Membrane Insertion of New AMPA Receptors and LTP in Cultured Hippocampal Neurons

Neuron, 2001
Wei-yang Lu, H. Man, W. Ju, W. Trimble, J. Macdonald, Yu Tian Wang   +5 more
semanticscholar   +1 more source

Deficiency of the Synaptic Adhesion Protein Leucine‐Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish

Acta Physiologica, Volume 241, Issue 5, May 2025.
ABSTRACT Aim Leucine‐rich repeat transmembrane proteins (LRRTMs) are synaptic adhesion proteins that regulate synapse development and function. They interact transsynaptically with presynaptic binding partners to promote presynaptic differentiation. Polymorphisms of LRRTM4, one of the four members of this protein family, have been linked to multiple ...
Eva Tatzl, Giulia Petracco, Isabella Faimann, Marco Balasso, Agnes Anna Mooslechner, Thomas Bärnthaler, Giovanny Rodriguez‐Blanco, Florian Reichmann   +7 more
wiley   +1 more source

Positive allosteric modulation of AMPA receptors via PF4778574 leads to reduced demyelination and clinical disability in experimental models of multiple sclerosis. [PDF]

Front Immunol
Sindi M, Dietrich M, Klees D, Gruchot J, Hecker C, Silbereis J, Issberner A, Hartung HP, Ruck T, Stark H, Kurz T, Küry P, Meuth SG, Albrecht P.   +13 more
europepmc   +1 more source

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

Nature, 2008
K. L. Conrad, Kuei Yuan Tseng, Jamie L. Uejima, Jeremy M. Reimers, Li-jun Heng, Y. Shaham, M. Marinelli, M. Wolf   +7 more
semanticscholar   +1 more source

Neuroprotection for neonatal hypoxic–ischemic encephalopathy: A review of novel therapies evaluated in clinical studies

Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 591-599, May 2025.
Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan, Cheryl C. Hawkins, Benjamin V. Rodrigues, Marie‐Coralie Cornet, Fernando F. Gonzalez, Yvonne W. Wu   +5 more
wiley   +1 more source

Roles of AMPA receptors in social behaviors. [PDF]

Front Synaptic Neurosci
Xu QW, Larosa A, Wong TP.
europepmc   +1 more source