Results 91 to 100 of about 10,352,886 (166)

Speeding stroke recovery? A systematic review of amphetamine after stroke [PDF]

, 2009
Introduction: The use of drugs to enhance recovery (“rehabilitation pharmacology”) has been assessed. Amphetamine can improve outcome in experimental models of stroke, and several small clinical trials have assessed its use in stroke.
Nikola Sprigg, Sprigg, Nikola, Philip M.W. Bath, Bath, Philip M.W.   +3 more
core   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms

Molecules, 2019
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors
Claudia Calpe-López, M. Pilar García-Pardo, Maria A. Aguilar   +2 more
doaj   +1 more source

Sibling Coping Provision, Negative Life Events, and Substance Use

Family Relations, EarlyView.
ABSTRACT Objective This study examined sibling coping provision as a moderator between negative life events and emerging adult substance use. Background Greater frequency of negative life events can increase substance use in emerging adulthood. As siblings often use their relationship to cope with stress, the ways in which emerging adults interact with
Derek D. Morgan, Sarah Killoren, Christy R. Rogers   +2 more
wiley   +1 more source

Stigmatising substance‐related language in the electronic health records of hospitalised patients after addiction consult service implementation

Internal Medicine Journal, EarlyView.
Abstract Objectives Stigmatising language about patients with substance use disorders (SUD) is common in healthcare settings and negatively impacts patient care. Addiction consult services are associated with improved clinician attitudes and less stigmatising views towards patients with SUD.
Ryder Cuppett, Justin Birge, Kristin Daniel, Alëna A. Balasanova   +3 more
wiley   +1 more source

Increased levels of cocaine and amphetamine regulated transcript in two animal models of depression and anxiety

Neurobiology of Disease, 2009
The neurobiological bases of mood disorders remain elusive but both monoamines and neuropeptides may play important roles. The neuropeptide cocaine and amphetamine regulated transcript (CART) was shown to induce anxiety-like behavior in rodents, and ...
Sara Wiehager, Daniela I. Beiderbeck, Susanne H.M. Gruber, Aram El-Khoury, Jackie Wamsteeker, Inga D. Neumann, Åsa Petersén, Aleksander A. Mathé   +7 more
doaj   +1 more source

Treating parents with ADHD and their children (TPAC): a hybrid effectiveness‐implementation, randomized controlled trial

Journal of Child Psychology and Psychiatry, EarlyView.
Background Attention‐Deficit/Hyperactivity Disorder (ADHD) is highly heritable; thus, parents and children frequently experience ADHD‐related impairments. Parent ADHD is associated with poorer developmental and treatment outcomes for children with ADHD, in part due to executive functioning and emotion regulation difficulties that interfere with ...
Andrea Chronis‐Tuscano, Nadia Bounoua, Christina M. Danko, Daniel Almirall, Joyce H.L. Lui, Donna Marschall, Daria Taubin, Hong N.T. Bui, Nicholas P. Marsh, Lisa Efron, Julia Dorfman, Nicole E. Lorenzo, Melissa Dvorsky, Ian M. Bennett, Shireen M. Atabaki, Adelaide S. Robb   +15 more
wiley   +1 more source

Mental health problems as mediators between childhood trauma and cardiometabolic risk behaviours in the 2004 Pelotas Birth Cohort

Journal of Child Psychology and Psychiatry, EarlyView.
Background Childhood trauma is associated with greater engagement in health risk behaviours (HRBs) that predispose to cardiometabolic disease. However, the mechanisms underlying these associations remain poorly understood. Mental health problems are hypothesised to mediate links between trauma and HRBs, but prospective evidence is limited, particularly
Sophie Townend, Gemma Hammerton, Graeme Fairchild, Megan Bailey, Jon Heron, Abigail Fraser, Luciana Tovo‐Rodrigues, Iná S. Santos, Aluísio J.D. Barros, Inácio Crochemore‐Silva, Sarah L. Halligan, Alicia Matijasevich   +11 more
wiley   +1 more source

The Impact of Dexamphetamine Treatment for Obesity on Executive Function: A Double-Blind Randomised Controlled Pilot Study

Brain Sciences
Background: Amphetamines increase dopamine levels in mid-brain regions which, in turn, impact top-down executive function. Repeated exposure is linked to substance use disorders.
Antoinette Poulton, Natalie Gauci, Hazer Khalifa, Emily J. Hibbert, Alison S. Poulton   +4 more
doaj   +1 more source

Cannabis Use Among People Aged 65 and Older: Results From an Intercept Survey in New York City

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Cannabis use among older adults has increased in recent years. Age‐related physiological changes, socio‐ecological factors, and medications may exacerbate potential adverse effects of cannabis and complicate the detection of cannabis use disorder (CUD) in older adults.
Benjamin H. Han, Krish Jagasia, Tyler Simi, Nina Abukahok, Joseph J. Palamar   +4 more
wiley   +1 more source