Results 111 to 120 of about 10,352,886 (166)

Amphetamine-Induced Δ[¹¹C]FLB457 BP_ND in Genotyped Healthy Subjects.

, 2016
The bar graph shows the amphetamine-induced reduction of [11C]FLB 457 BPND in cortical regions of interest comparing Val/Val (white bars), Val/Met (shaded bars), and Met/Met (black bars) genotyped healthy subjects.
Maureen A. May (2847386), Kelli Fasenmyer (2847377), Divya Tumuluru (2847383), Rajesh Narendran (304516), Michael L. Himes (2847380), W. Gordon Frankle (331205), Vishwajit L. Nimgaonkar (28735), Kodavali V. Chowdari (260174)   +7 more
core   +1 more source

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Elevated Levels of Blood Neurofilament Light Chain in Substance‐Using Populations: A Systematic Review and Meta‐Analysis

Psychiatry and Clinical Neurosciences, EarlyView.
Substance‐use disorders are increasingly linked to structural and functional brain alterations consistent with neuroaxonal injury. Neurofilament light chain (NfL) is a sensitive blood‐based marker of axonal damage, but evidence in substance‐using populations remains fragmented.
João Antônio Valadão Leal, Thiago Wendt Viola, Rodrigo Grassi‐Oliveira   +2 more
wiley   +1 more source

Evaluating drug law enforcement interventions directed towards methamphetamine in Australia [PDF]

, 2012
This report presents a preliminary analysis comparing the costs and impacts different types of law enforcement have on methamphetamine use. Methamphetamine belongs in the class of stimulant drugs referred to as Amphetamine Type Stimulants (ATS).
David Bright, Wendy Gong
core  

Using an Adapted Job Demands–Resources Model to Examine the Use of Legal, Prescription, and Illegal Drugs for Cognitive Enhancement in the Working Population in Germany

Sociological Inquiry, EarlyView.
Chronic stress is a global issue with detrimental effects on health and productivity, often leading individuals to adopt health‐related coping strategies. This study uses an adapted Job Demands–Resources model to examine how various job demands and resources impact perceived stress and, consequently, the use of legal, prescription, and illegal drugs ...
Sebastian Sattler, Mareike Reimann, Myriam Baum, Nina Hänel   +3 more
wiley   +1 more source

Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way

Neurobiology of Disease
Addiction is a chronic and severe mental disorder with high gender- and sex-specificity. However, the pathogenesis of this disorder is not fully elucidated, and no targeted pharmacotherapy is available. A growing body of evidence points out the potential
Liubov S. Kalinichenko, Iulia Zoicas, Anne-Marie Bienia, Clara Bühner, Julia Robinson, Joshua Kütemeyer, Annika Labonte, Thadshajiny Raveendran, Lena Warth, Irena Smaga, Malgorzata Filip, Volker Eulenburg, Cosima Rhein, Anna Fejtova, Erich Gulbins, Johannes Kornhuber, Christian P. Müller   +16 more
doaj   +1 more source

Psychotropic medication and the fetal brain

The Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

Identification of TREK channels in mouse intracardiac ganglion neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Role of TWIK‐related K+ (TREK) channels in intracardiac ganglion neurons. CD‐1 mice were used to establish primary cultures of intracardiac neurons for immunochemical characterization and patch‐clamp electrophysiology. Intracardiac neurons express functional TREK channels, which modulate neuronal excitability by regulating ...
Ana Campos‐Rios, Salvador Herrera‐Perez, Manuela Rodriguez‐Castañeda, Diego Ameal‐Tedin, Marta Alvarez‐Rodriguez, David Blanco‐Remesar, Ainhoa Rodriguez‐Tebar, Encarnación De Miguel, Ana Covelo, J. Antonio Lamas   +9 more
wiley   +1 more source

Amphetamine usage, misuse, and addiction processes: an overview

, 2016
Amphetamine (D-amphetamine, dextroamphetamine) is a synthetic drug that possesses psychostimulant and performance-enhancing properties. Amphetamine has some medical indications, especially for those conditions characterized by reduced attention. However,
SIMOLA, NICOLA, CARTA, MANOLO, Manolo Carta, Nicola Simola   +3 more
core   +1 more source

HIV Testing and Care Among Publicly Insured Enrollees With Schizophrenia: Is There a Benefit to Dual Eligibility?

Psychiatric Research and Clinical Practice, EarlyView.
Background Patients with schizophrenia experience gaps in the human immunodeficiency virus (HIV) care continuum. We examined the impact of dual enrollment in Medicare upon HIV testing and retention among Medicaid‐enrolled patients with schizophrenia.
Karly Murphy, Marilyn D. Thomas, Paola Alonso‐Fraire, Alexander R. Bazazi, Priya Dahiya, Mark Olfson, Francine Cournos, Emily Arnold, James Dilley, Paul Wesson, Richard Hermida, James Walkup, Stephen Crystal, Christina Mangurian   +13 more
wiley   +1 more source