Results 121 to 130 of about 10,352,886 (166)

Influence of the gut microbiome on appetite-regulating neuropeptides in the hypothalamus: Insight from conventional, antibiotic-treated, and germ-free mouse models of anorexia nervosa

Neurobiology of Disease
Recent research highlights the profound impact of the gut microbiome on neuropsychiatric disorders, shedding light on its potential role in shaping human behavior.
Radka Roubalová, Petra Procházková, Tereza Kovářová, Janet Ježková, Tomáš Hrnčíř, Helena Tlaskalová-Hogenová, Hana Papežová   +6 more
doaj   +1 more source

Effects of L-Amphetamine on the Central Neurons of the Snail

, 2009
The effects of l-amphetamine on the spontaneous firing of central neurons of African snails (Achatina fulica Ferussac) were studied electrophysiologically. The effects of dopamine, noradrenaline, d- amphetamine, and methamphetamine on the central neurons
Huang, Shiang-Suo; Chuang, Yao-Chin; Chen, Yi-Hung; Tsai, Ming-Cheng, 蔡明正   +1 more
core  

Amphetamine-Induced Excitations Predominate in Single Neostriatal Neurons Showing Motor-Related Activity

, 1989
Neostriatal single-unit activity was recorded in freely moving rats. A majority (62%) of the 24 recorded neurons were activated during motor behavior such as locomotion (n = 11) or head movements (n = 4). The behavioral response to amphetamine (1.0 mg/kg)
Haracz, John L., Rebec, George V., Greenberg, Jordan, Tschanz, JoAnn T.   +3 more
core   +1 more source

Dose‐dependent efficacy and safety of centanafadine in patients with attention‐deficit/hyperactivity disorder: A systematic review of the latest evidence

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Abstract Centanafadine is a multimodal norepinephrine–dopamine–serotonin reuptake inhibitor (NDSRI) that has been evaluated for the treatment of attention‐deficit/hyperactivity disorder (ADHD) across pediatric, adolescent, and adult populations. This systematic review aimed to evaluate the efficacy, safety, and tolerability of centanafadine compared ...
Daud Gul, Sonia Khan, Kushal Baral, Ziad Saber, Arindam Ghosh, Eemaz Nathaniel, Onuwabhagbe Daniel Omomhenle, Nathaniel Oluwakayode Oyedeji, Lana Omar Saed Alkhatib, Lina Jamal Amin Sa'doun, Austin Nwawueze, Muhammad Naveed Ullah Khan, Raouf Khan   +12 more
wiley   +1 more source

Amphetamine users and crime in Western Australia, 1999–2009 [PDF]

, 2012
This current study aims to examine the relationship between amphetamine use and crime among police detainees in Western Australia. Further, the study provides a brief profile of detainee amphetamine users and compares this with the profile of a non ...
Natalie Gately, Jennifer Fleming, Robyn Morris   +2 more
core  

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, Volume 183, Issue 23, Page 6787-6800, December 2026.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

A Mechanistic Study on Urine Retention in D-Amphetamine Addicts

, 2017
Chronic amphetamine intake leads to neurogenic bladder and chronic urinary retention. The mechanism underlying persistent urinary retention is unclear.
陳宜明;張榮珍, Chiu, Hui-Fang;Cheng, Jen-Kun;Lin, Pu-Hua;Chang, Jung-Chen;Chen, I-Ming;Lin, Ching-I;Chang, Wei-Pin;Lin, Chia-Hsien   +1 more
core   +1 more source

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

Annals of Neurology, Volume 100, Issue 5, Page 1023-1027, November 2026.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau, Sebastien Arthaud, Leila Langbour, Silvia Melzi, Aurelie Richard‐Mornas, Hannah Doudoux, Benjamin Rolland, Laure Peter‐Derex, Christelle Peyron   +8 more
wiley   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, Volume 18, Issue 11, Page 1361-1373, November 2026.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Assessing the use of ASAP‐MS for Screening a UK Pub for Illicit Drug Substances

Journal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT Illicit drug use in social environments, such as pubs and bars, has become an increasingly significant issue for public health and safety. These venues often provide a setting where individuals may engage in recreational drug use, resulting in their residual presence on high‐contact surfaces.
Andriana Michailidis, Simone Mathias, Eloise Edgar‐Gibson, David Douce, Victoria Starkie, Melanie Bailey, Patrick Sears   +6 more
wiley   +1 more source