Results 61 to 70 of about 95,889 (290)
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2019 In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate.
Benivaldo Ramos Ferreira Terceiro +8 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source
A Degradable Device for Sustainable Capillary Blood Sampling
Advanced Materials Technologies, EarlyView.The device features a compostable 3D‐printed storage compartment for liquid blood collection and a degradable, poly(ɛ‐caprolactone)‐coated magnesium microneedle patch hidden within a suction cup. Manual compression deploys the MNs, creating small skin punctures, and the subsequent release of compression generates the negative pressure required for ...
Nicole Zoratto +5 more
wiley +1 more source
Advanced Science, EarlyView.This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan +11 more
wiley +1 more source
Antibiotics and antifungals in silicone oil
International Journal of Retina and Vitreous, 2019 Background Antimicrobials may be injected into silicone oil-filled eyes with endophthalmitis, but the interaction with oil is unclear. The purpose of the experiment is to determine whether vancomycin, amikacin, and amphotericin B mix with silicone oil ...
Ella H. Leung, J. Timothy Stout
doaj +1 more source
Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype
Advanced Science, EarlyView.This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez +20 more
wiley +1 more source
Antifungal Activity of Silver Nanoparticles, Copper Nanoparticles, Their Combination and with Amphotericin B against Candida glabrata In vitro and In vivo [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017 Background: Candida glabrata is the fourth most common cause of blood infection in America and, due to its resistance to amphotericin B, we have to look for new therapies.
Mahdi Jafarzadeh +2 more
doaj
In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis
Frontiers in Bioengineering and Biotechnology, 2020 The purpose of our research was the development of Amphotericin B-loaded in situ gelling nanofibers for the treatment of keratomycosis. Different formulation strategies were applied to increase the drug load of the sparingly water-soluble Amphotericin B ...
Benedikt Göttel +7 more
doaj +1 more source
Advanced Science, EarlyView.Co‐administration with MHC class I‐ and II‐restricted neoantigens encoding mRNA‐based personalized cancer vaccines in a mouse CRC model can induce antigen‐specific immune responses and anti‐cancer effects. Notably, vaccination at an early stage of cancer development can have potent anti‐cancer effects. Furthermore, combining mRNA with immune checkpoint
Seongje Cho +26 more
wiley +1 more source