Results 71 to 80 of about 407,170 (392)

Celecoxib Enhances the Efficacy of Low-Dose Antibiotic Treatment against Polymicrobial Sepsis in Mice and Clinical Isolates of ESKAPE Pathogens

Frontiers in Microbiology, 2017
Treatment of multidrug resistant bacterial infections has been a great challenge globally. Previous studies including our study have highlighted the use of celecoxib, a non-steroidal anti-inflammatory drug in combination with antibiotic has decreased the
Madhavi Annamanedi, Gajapati Y. N. Varma, K. Anuradha, Arunasree M. Kalle   +3 more
doaj   +1 more source

Clinical characteristics of bloodstream infections due to ampicillin-sulbactam-resistant, non-extended-spectrum-β-lactamase-producing Escherichia coli and the role of TEM-1 hyperproduction [PDF]

, 2011
Ampicillin-sulbactam is commonly used as an empirical therapy for invasive infections where Escherichia coli is a potential pathogen. We evaluated the clinical and microbiologic characteristics of bloodstream infection due to E. coli, with focus on cases
Adams-Haduch, JM, Doi, Y, Jones, M, Pasculle, AW, Paterson, DL, Qureshi, ZA, Shutt, KA, Sidjabat, HE, Tian, GB, Waltner-Toews, RI   +9 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Camellia-sinensis- and Cocos-nucifera-Derived Gold Nanoparticles for Treatment of Infections Caused by Antibiotic-Resistant Staphylococcus aureus 

Materials Proceedings, 2023
The development of bacterial resistance toward existing antibiotics is a universal problem for human and animal health as well as for food security. In an attempt to overcome this problem, nanotechnology has contributed in the form of nanoformulations ...
Saman Anwar, Sidra Altaf, Muhammad Saif Ur Rehman Babar, Bilal Aslam, Humaira Muzaffar, Arslan Iftikhar   +5 more
doaj   +1 more source

Pseudomonas aeruginosa bacteremia in patients undergoing liver transplantation: An emerging problem [PDF]

, 1991
In our institution, Pseudomonas aeruginosa bacteremia appeared to occur with increasing frequency in patients undergoing liver transplantation. We thus conducted a prospective study to define risk factors and outcome in these patients.
Korvick, JA, Marsh, JW, Starzl, TE, Yu, VL   +3 more
core  

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

Advanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel, Maria Alessandra Martini, Marius Stoeckle, Annika J. Weber, Kersten S. Rabe, Christof M. Niemeyer   +5 more
wiley   +1 more source

Apigenin and Ampicillin as Combined Strategy to Treat Severe Streptococcus suis Infection

Molecules, 2021
As an important zoonotic pathogen, Streptococcus suis (S. suis) can cause a variety of diseases both in human and animals, especially Streptococcal toxic shock-like syndrome (STSLS), which commonly appears in severe S. suis infection.
Hao Lu, Chenchen Wang, Wenjia Lu, Xiaodan Li, Zhaoyuan Wu, Gaoyan Wang, Wenqi Dong, Chen Tan, Manli Liu   +8 more
doaj   +1 more source

Ampicillin permeation across OmpF, the major outer-membrane channel in Escherichia coli

Journal of Biological Chemistry, 2018
The outer cell wall of the Gram-negative bacteria is a crucial barrier for antibiotics to reach their target. Here, we show that the chemical stability of the widely used antibiotic ampicillin is a major factor in the permeation across OmpF to reach the ...
Ishan Ghai, Harsha Bajaj, Jayesh Arun Bafna, Hussein Ali El Damrany Hussein, M. Winterhalter, R. Wagner   +5 more
semanticscholar   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

Seasonal variations in antibiotic resistance gene transport in the Almendares River, Havana, Cuba [PDF]

, 2012
Numerous studies have quantified antibiotic resistance genes (ARG) in rivers and streams around the world, and significant relationships have been shown that relate different pollutant outputs and increased local ARG levels.
Charles W Knapp, Charles W Knapp, David eWerner, David W eGraham, Emma eBowen, Lazaro eLima, Susana eOlivares-Rieumont   +6 more
core   +2 more sources