Results 81 to 90 of about 3,637,465 (291)

Resistance to ampicillin. [PDF]

open access: yesJournal of Clinical Pathology, 1970
R J, Holt, R L, Newman
openaire   +2 more sources

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

BACTERIOLOGICAL STATUS OF PASTEURIZED MARKET MILK IN THRISSUR AND ANTIBIOGRAM OF ESCIIERICHIA COLI ISOLATES [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2014
Cent per cent of isolates were sensitive to chloramphenicol and gentamicin and 72 per cent of isolates were sensitive to sulphafurazole. None of the isolates showed resistance to these three antimicrobial agents.
C. Latha, E. Nanu, B. Sunil
doaj  

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

open access: yesAdvanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen   +9 more
wiley   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang   +8 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

Studies on in vitro interaction of ampicillin and fresh garlic extract against Staphylococcus aureus by checkerboard method

open access: yesAncient Science of Life, 2013
Objective: Staphylococcus aureus has largely developed resistance to the multiple antimicrobial agents. Garlic (Allium sativum) is claimed to retard development of resistance and produce synergy with conventional antimicrobial agents.
R Pillai   +2 more
doaj   +1 more source

Optimized Selenium‐Doped Nanocomposites for Enhanced Polymer Gel Performance in Permeability Reduction

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Excessive water production in mature oil fields necessitates robust shut‐off treatments, yet conventional polymer gels often fail under high‐temperature and high‐salinity conditions. This study aims to enhance gel thermal stability and mechanical strength by incorporating selenium‐doped Ag/AgO–ZnO nanocomposites synthesized via a novel green ...
Fadhil F. Sead   +8 more
wiley   +1 more source

Expansion of Salmonella Typhi clonal lineages with ampicillin resistance and reduced ciprofloxacin susceptibility in Eastern China

open access: yesInfection and Drug Resistance, 2019
Dingfeng Lv,1 Danyang Zhang,2 Qifa Song21Department of Clinical Laboratory, Ningbo First Hospital, Ningbo, Zhejiang Province, People’s Republic of China; 2Department of Microbiology, Ningbo Municipal Centre for Disease Control and Prevention ...
Lv D, Zhang D, Song Q
doaj  

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