Results 51 to 60 of about 218,037 (308)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

ImageGP: An easy‐to‐use data visualization web server for scientific researchers

iMeta, 2022
Data visualization plays a crucial role in illustrating results and sharing knowledge among researchers. Though many types of visualization tools are widely used, most of them require enough coding experience or are designed for specialized usages, or ...
Tong Chen, Yong‐Xin Liu, Luqi Huang
doaj   +1 more source

Number of reads per amplicon versus amplicon length.

, 2017
The number of reads per amplicon has little relationship with amplicon length. Long amplicons are represented.
Shilpa Sood (3611885), Randall J. Wisser (3259779), Tiffany M. Jamann (3611888), James B. Holland (195686)   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Evidence of WNV infection in migratory birds passing through Xinjiang, China, using viral genome amplicon approach

Frontiers in Microbiology
The West Nile virus (WNV) is a mosquito-borne virus of the Flaviviridae family that is transmitted through the mosquito-migratory bird-mosquito cycle.
Kunsheng Tao, Chan He, Tong Zhang, Changguang Xiao, Lifei Du, Zongjie Li, Donghua Shao, Jianchao Wei, Beibei Li, Yafeng Qiu, Zhiyong Ma, Ke Liu   +11 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Yellow Fever Outbreak, Imatong, Southern Sudan

Emerging Infectious Diseases, 2004
In May 2003, the World Health Organization received reports about a possible outbreak of a hemorrhagic disease of unknown cause in the Imatong Mountains of southern Sudan.
Clayton O. Onyango, Victor O. Ofula, Rosemary C. Sang, Samson L. Konongoi, Abdourahmane Sow, Kevin M. De Cock, Peter M. Tukei, Fredrick A. Okoth, Robert Swanepoel, Felicity J. Burt, Norman C. Waters, Rodney L. Coldren   +11 more
doaj   +1 more source

Amplicon alignments

, 2019
Amplicon ...
Pedro Andrade (806677), Marsik, Petr, Bosakova, Zuzana, Uller Tobias (6331988), Pinho, Catarina, Nathalie Feiner (3189108), Carretero, Miguel A., Daniele Salvi (314127), Pereira, Paulo, Catarina Pinho (89687), Zuzana Bosakova (3595646), Enrique Font (2657464), While, Geoffrey M., Adriana Bellati (3257547), Guillem Pérez i de Lanuza (3200358), Leif Andersson (42573), Pérez i de Lanuza, Guillem, Paulo Pereira (359404), Bunikis, Ignas, Sandra Afonso (469330), Petr Marsik (4044650), Carneiro, Miguel, Miguel A. Carretero (486979), Salvi, Daniele, Rubin, Carl-Johan, Soler, Lucile, Jindřich Brejcha (6331979), Afonso, Sandra, Carl-Johan Rubin (77551), Lucile Soler (6331985), Brejcha, Jindřich, Tobias, Uller, Pellitteri-Rosa, Daniele, Andersson, Leif, Stephen J. Sabatino (3255885), Miguel Carneiro (133770), Andrade, Pedro, Paupério, Francisco, Daniele Pellitteri-Rosa (3257544), Font, Enrique, Feiner, Nathalie, Geoffrey M. While (690012), Francisco Paupério (6331982), Sabatino, Stephen J., Bellati, Adriana, Ola Wallerman (255908), Ignas Bunikis (89974), Wallerman, Ola   +47 more
core   +1 more source

SESAME (SEquence Sorter & AMplicon Explorer): genotyping based on high-throughput multiplex amplicon sequencing [PDF]

Bioinformatics, 2010
Abstract Summary: Characterizing genetic diversity through genotyping short amplicons is central to evolutionary biology. Next-generation sequencing (NGS) technologies changed the scale at which these type of data are acquired. SESAME is a web application package that assists genotyping of multiplexed individuals for several markers ...
Meglécz, Emese, Piry, Sylvain, Desmarais, Erick, Galan, Maxime, Gilles, André, Guivier, Emmanuel, Pech, Nicolas, Martin, Jean-François   +7 more
openaire   +5 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source