Results 61 to 70 of about 1,296 (182)
Amrinone suppresses the synthesis of tumor necrosis factor-alpha in human mononuclear cells
, 1994 Tumor necrosis factor-alpha (TNF) exerts a wide spectrum of biological activities and contributes to the pathophysiology of septic shock. Elevated circulating levels of TNF have also been reported in patients with severe chronic heart failure. We studied
Endres, S +2 more
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Echocardiographic evaluation of cardiovascular effects of amrinone
, 1984 Amrinone, a new inotropic drug, was infused at a dosage of 2.5 mg/kg body weight in 14 patients affected by dilatative cardiomyopathy in New York Heart Association (NYHA) functional class III and IV.
MATTIOLI, Giorgio +5 more
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Amrinone potentiates catecholamine-induced lipolysis in fat cells
, 1989 Am&tone, a bipyridine derivative, exerts a positive inotropic action in vitro 11-31 and in viuo 141. In addition, the drug produces a marked relaxation of vascular [5,6] and intestinal [5,7-91 smooth muscle.
Gaion, R M +4 more
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Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury
, 2005 Background: The preventive effect of amrinone on ischaemia/reperfusion (I/R) injury has been shown in the medical literature. The purpose of the present study was to investigate the preventive effect of amrinone on I/R injury of the small bowel of the ...
Kale, N +11 more
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, 1984 In rabbit papillary muscles, the pronounced inotropic effect of amrinone (0.4–0.8 mg/mL) observed at low stimulation frequencies (0.1–0.5 Hz) diminished as the frequency was increased to 1.0–2.0 Hz. Reversal of the negative inotropic effect of halothane
Ben F. Rusy, Hirochika Komai
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Combination of norepinephrine and amrinone in the treatment of endotoxin shock
, 1989 The combination of phosphodiesterase inhibitors and adrenergic agents represents an interesting option to increase cardiac output in acute circulatory failure.
Coussaert, Edouard +6 more
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Effect of amrinone on right ventricular function: predominance of afterload reduction.
, 1986 Although the bipyridine agent amrinone is reported to have a positive inotropic effect on the left ventricle, the effect of this drug on right ventricular contractility in the clinical setting is unknown.
M J Aronovitz +5 more
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Effects of amrinone on the contractile behaviour of frog striated muscle fibres
, 1985 The effects of amrinone (0.005–2.1 mM) were studied on isolated single muscle fibres of the frog (0.6–4.3 °C). In the concentrations used amrinone potentiated the isometric twitch, increased the initial rate of force development and prolonged the time to
K. A. P. EDMAN +3 more
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, 1992 This study analyses the effects of Amrinone (bipyridine derivative with phosphodiesterase inhibitor properties) on the myofibrillar apparatus of rat myocardium. Thin trabeculae were isolated from the right ventricle and chemically demembranated.
M. CANEPARI +8 more
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