Results 61 to 70 of about 1,170 (185)

Effects of amrinone on the contractile behaviour of frog striated muscle fibres

, 1985
The effects of amrinone (0.005–2.1 mM) were studied on isolated single muscle fibres of the frog (0.6–4.3 °C). In the concentrations used amrinone potentiated the isometric twitch, increased the initial rate of force development and prolonged the time to
K. A. P. EDMAN, Månsson, Alf,, ALF MÅNSSON, Edman, K A P,   +3 more
core   +1 more source

Comparison of Hemodynamic Effects between Dobutamine and Amrinone in the Patients with Pulmonary Hypertension

, 1997
BACKGROUND Dobutamine and amrinone, phosphodiesterase-III inhibitor, are known to have both inotropic and vasodilatory properties. We evaluated the effects of both drugs on systemic and pulmonary hemodynamics in patients with pulmonary hypertension (PH).
곽영란
core  

Diminished inotropic response to amrinone in ventricular myocytes from myopathic hamsters is linked to depression of high-gain Ca2+-induced Ca2+ release

, 2004
This study investigates whether amrinone (100-1000 μM), a phosphodiesterase-III inhibitor, can alleviate depression of contractions in ventricular myocytes from prefailure cardiomyopathic (CM) hamsters (80-100 days). Cell shortening and ion currents were
Ferrier, Gregory R., Howlett, Susan E., Xiong, Wei   +2 more
core   +1 more source

Effects of Amrinone on shortening velocity, force development and ATPase activity of demembranated preparations of rat ventricular myocardium.

, 1992
This study analyses the effects of Amrinone (bipyridine derivative with phosphodiesterase inhibitor properties) on the myofibrillar apparatus of rat myocardium. Thin trabeculae were isolated from the right ventricle and chemically demembranated.
M. CANEPARI, CANEPARI, MONICA, CAPPELLI, VANDA, R. BOTTINELLI, V. CAPPELLI, C. Reggiani, S. E. Mörner, BOTTINELLI, ROBERTO, S. E. J. N. MÖRNER   +8 more
core   +1 more source

Effects of amrinone, a cardiotonic drug, on calcium movements in dog erythrocytes.

, 1980
Dog erythrocytes (RBC) have a system for passive Ca and Na movements that resembles the Ca-Na exchanger first described in cardiac muscle. Amrinone, a new cardiotonic drug active in humans with congestive heart failure, is shown to stimulate net Ca ...
J R Harper, J C Parker, Harper, J R, Parker, J C   +3 more
core   +1 more source

Effects of amrinone, a phosphodiesterase inhibitor, on right ventricular/arterial coupling immediately after cardiac operations

, 1998
Objective: Amrinone, a selective phosphodiesterase III inhibitor, is reported to have a potent inotropic effect on the left ventricle, but the effects of this drug on right ventricular contractility in the clinical setting are unknown.
Yasui, Hisataka, Morita, Shigeki, Tanoue, Yoshihisa, Tominaga, Ryuji, Kawachi, Yoshito, Ochiai, Yoshie   +5 more
core   +1 more source

Oral amrinone in refractory congestive heart failure.

, 1980
The acute effects of an oral preparation of amrinone, a recently synthesized cardiotonic agent, were assessed noninvasively in nine patients who had advanced heart failure that persisted despite treatment with digitalis, diuretic drugs and afterload ...
Smith, T W, Holman, B L, Benotti, J R, Grossman, W, Wynne, J, Malacoff, R F, Curfman, G D, Braunwald, E   +7 more
core  

Cardiotonic bipyridine amrinone slows myosin-induced actin filament sliding at saturating [MgATP]

, 2003
Previously reported effects of amrinone on skeletal muscle function suggest that the drug reduces the rate constant of myosin cross-bridge dissociation.
Arner, Anders, Mansson, A, Klinth, J
core   +2 more sources

Temperature management for deliberate mild hypothermia during neurosurgical procedures. [PDF]

Fukushima J Med Sci, 2022
Inoue S.
europepmc   +1 more source

Home Intermittent Amrinone Infusions in Terminal Congestive Heart Failure

, 1989
The prevalence of congestive heart failure (CHF) and its progressive degenerative course continue to generate pressure for alternative, more effective means of treatment. A confluence of factors, including the number of Americans with CHF, the spiraling
Richard J. Baptista, Joanne Perri-Lafrancesca, Francis P. Mitrano   +2 more
core   +1 more source