Results 51 to 60 of about 1,170 (185)
Echocardiographic evaluation of cardiovascular effects of amrinone
, 1984 Amrinone, a new inotropic drug, was infused at a dosage of 2.5 mg/kg body weight in 14 patients affected by dilatative cardiomyopathy in New York Heart Association (NYHA) functional class III and IV.
MATTIOLI, Giorgio +5 more
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Amrinone potentiates catecholamine-induced lipolysis in fat cells
, 1989 Am&tone, a bipyridine derivative, exerts a positive inotropic action in vitro 11-31 and in viuo 141. In addition, the drug produces a marked relaxation of vascular [5,6] and intestinal [5,7-91 smooth muscle.
Gaion, R M +4 more
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Clinical applications of amrinone
Journal of Cardiothoracic Anesthesia, 1989 A bipyridine derivative, amrinone is a noncatecholamine, nonglycoside alternative in the treatment of perioperative myocardial dysfunction. A type-3 phosphodiesterase enzyme inhibitor, amrinone combines positive inotropic support with systemic and pulmonary vasodilation.
openaire +2 more sources
Effect of amrinone on mucosal permeability in experimental intestinal ischaemia/reperfusion injury
, 2005 Background: The preventive effect of amrinone on ischaemia/reperfusion (I/R) injury has been shown in the medical literature. The purpose of the present study was to investigate the preventive effect of amrinone on I/R injury of the small bowel of the ...
Kale, N +11 more
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, 1984 In rabbit papillary muscles, the pronounced inotropic effect of amrinone (0.4–0.8 mg/mL) observed at low stimulation frequencies (0.1–0.5 Hz) diminished as the frequency was increased to 1.0–2.0 Hz. Reversal of the negative inotropic effect of halothane
Ben F. Rusy, Hirochika Komai
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Effect of amrinone on right ventricular function: predominance of afterload reduction.
, 1986 Although the bipyridine agent amrinone is reported to have a positive inotropic effect on the left ventricle, the effect of this drug on right ventricular contractility in the clinical setting is unknown.
M J Aronovitz +5 more
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Vesnarinone and amrinone reduce the systemic inflammatory response syndrome
, 1999 Objective: The systemic inflammatory response is an important cause of organ dysfunction. The present study tested the hypothesis that 2 clinically used agents, amrinone and vesnarinone, would decrease inflammation and cardiac dysfunction in a relevant ...
del Nido, Pedro J. +8 more
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Combination of norepinephrine and amrinone in the treatment of endotoxin shock
, 1989 The combination of phosphodiesterase inhibitors and adrenergic agents represents an interesting option to increase cardiac output in acute circulatory failure.
Coussaert, Edouard +6 more
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, 1985 A number of uncontrolled studies have indicated that oral administration of amrinone, a phosphodiesterase inhibitor with potent positive inotropic effects in experimental preparations, may be beneficial in patients with chronic congestive heart failure ...
M Packer +6 more
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