Results 51 to 60 of about 1,296 (182)

Additive effects of dobutamine and amrinone on myocardial contractility and ventricular performance in patients with severe heart failure.

open access: yes, 1986
The effects of amrinone, dobutamine, and a combination of the two drugs on peak positive left ventricular dP/dt and left ventricular performance were evaluated in 11 patients with chronic congestive heart failure. When administered alone, both dobutamine
D Lucido, H Rutman, J Gage, T H LeJemtel
core   +1 more source

Efficacy cardiotonic medicines on the bioenergetic processes and endothelial dysfunction under coupled of heart failure and systemic inflammatory syndroms in

open access: yesКубанский научный медицинский вестник, 2016
The efficacy of cardiotonic drugs on the energy supply system and bioenergetic processes in failing myocardium under severe form heart failure (HF) coupled with systemic inflammatory response syndrom, has been studied in the randomized, controlled trial.
D. I. Ionov   +6 more
doaj  

Positive hemodynamic interaction between amrinone and diltiazem in anesthetized dogs

open access: yes, 1989
The direct negative inotropic actions of calcium channel blockers limit the use of these otherwise effective systemic and coronary vasodilators in patients with heart failure.
E. Dagher, C. Chartrand, L. Dumont
core   +1 more source

Effects of amrinone, a cardiotonic drug, on calcium movements in dog erythrocytes. [PDF]

open access: yes, 1980
Dog erythrocytes (RBC) have a system for passive Ca and Na movements that resembles the Ca-Na exchanger first described in cardiac muscle. Amrinone, a new cardiotonic drug active in humans with congestive heart failure, is shown to stimulate net Ca ...
J R Harper   +3 more
core   +1 more source

On the conformational structure of amrinone and milrinone

open access: yes, 1987
Based on the ab initio STO-3G method including geometry optimization, a conformational analysis of the bipyridine cardiotonics amrinone and milrinone was performed. The results indicate a considerably twisted structure for both molecules.
CIMIRAGLIA, Renzo, H. Hofmann
core   +1 more source

The role of amrinone in potential heart transplant patients with pulmonary hypertension [PDF]

open access: yes, 1989
Orthotopic heart transplantation is contraindicated in patients with pulmonary hypertension and an elevated pulmonary vascular resistance. In an attempt to make otherwise unacceptable patients possible candidates for heart transplantation, amrinone was ...
Deeb, G. Michael, Boiling, Steven F.
core   +1 more source

Clinical applications of amrinone

open access: yesJournal of Cardiothoracic Anesthesia, 1989
A bipyridine derivative, amrinone is a noncatecholamine, nonglycoside alternative in the treatment of perioperative myocardial dysfunction. A type-3 phosphodiesterase enzyme inhibitor, amrinone combines positive inotropic support with systemic and pulmonary vasodilation.
openaire   +2 more sources

Effects of Amrinone on the Systemic and Pulmonary Hemodynamics in Patients with Pulmonary Hypertension

open access: yes, 1996
BACKGROUND: Amrinone is a noncatecholamine, nonglycoside agent with both inotropic and vasodilatory properties and therefore seems suitable for therapy of right ventricular(RV) dysfunction.
곽영란
core   +1 more source

Effects of amrinone, a phosphodiesterase inhibitor, on right ventricular/arterial coupling immediately after cardiac operations [PDF]

open access: yes, 1998
Objective: Amrinone, a selective phosphodiesterase III inhibitor, is reported to have a potent inotropic effect on the left ventricle, but the effects of this drug on right ventricular contractility in the clinical setting are unknown.
Yasui, Hisataka   +5 more
core   +1 more source

Oral amrinone in refractory congestive heart failure.

open access: yes, 1980
The acute effects of an oral preparation of amrinone, a recently synthesized cardiotonic agent, were assessed noninvasively in nine patients who had advanced heart failure that persisted despite treatment with digitalis, diuretic drugs and afterload ...
Smith, T W   +7 more
core   +1 more source

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