Results 51 to 60 of about 1,296 (182)
The effects of amrinone, dobutamine, and a combination of the two drugs on peak positive left ventricular dP/dt and left ventricular performance were evaluated in 11 patients with chronic congestive heart failure. When administered alone, both dobutamine
D Lucido, H Rutman, J Gage, T H LeJemtel
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The efficacy of cardiotonic drugs on the energy supply system and bioenergetic processes in failing myocardium under severe form heart failure (HF) coupled with systemic inflammatory response syndrom, has been studied in the randomized, controlled trial.
D. I. Ionov +6 more
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Positive hemodynamic interaction between amrinone and diltiazem in anesthetized dogs
The direct negative inotropic actions of calcium channel blockers limit the use of these otherwise effective systemic and coronary vasodilators in patients with heart failure.
E. Dagher, C. Chartrand, L. Dumont
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Effects of amrinone, a cardiotonic drug, on calcium movements in dog erythrocytes. [PDF]
Dog erythrocytes (RBC) have a system for passive Ca and Na movements that resembles the Ca-Na exchanger first described in cardiac muscle. Amrinone, a new cardiotonic drug active in humans with congestive heart failure, is shown to stimulate net Ca ...
J R Harper +3 more
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On the conformational structure of amrinone and milrinone
Based on the ab initio STO-3G method including geometry optimization, a conformational analysis of the bipyridine cardiotonics amrinone and milrinone was performed. The results indicate a considerably twisted structure for both molecules.
CIMIRAGLIA, Renzo, H. Hofmann
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The role of amrinone in potential heart transplant patients with pulmonary hypertension [PDF]
Orthotopic heart transplantation is contraindicated in patients with pulmonary hypertension and an elevated pulmonary vascular resistance. In an attempt to make otherwise unacceptable patients possible candidates for heart transplantation, amrinone was ...
Deeb, G. Michael, Boiling, Steven F.
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Clinical applications of amrinone
A bipyridine derivative, amrinone is a noncatecholamine, nonglycoside alternative in the treatment of perioperative myocardial dysfunction. A type-3 phosphodiesterase enzyme inhibitor, amrinone combines positive inotropic support with systemic and pulmonary vasodilation.
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BACKGROUND: Amrinone is a noncatecholamine, nonglycoside agent with both inotropic and vasodilatory properties and therefore seems suitable for therapy of right ventricular(RV) dysfunction.
곽영란
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Effects of amrinone, a phosphodiesterase inhibitor, on right ventricular/arterial coupling immediately after cardiac operations [PDF]
Objective: Amrinone, a selective phosphodiesterase III inhibitor, is reported to have a potent inotropic effect on the left ventricle, but the effects of this drug on right ventricular contractility in the clinical setting are unknown.
Yasui, Hisataka +5 more
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Oral amrinone in refractory congestive heart failure.
The acute effects of an oral preparation of amrinone, a recently synthesized cardiotonic agent, were assessed noninvasively in nine patients who had advanced heart failure that persisted despite treatment with digitalis, diuretic drugs and afterload ...
Smith, T W +7 more
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