Buyang Huanwu Decoction Alleviates Bleomycin-Induced Pulmonary Fibrosis via Wnt/β-catenin and TGF-β1/Smad Pathways. [PDF]
Chem BiodiversThe supernatant fraction of Buyang Huanwu Decoction, obtained by ethanol precipitation, demonstrates superior efficacy against pulmonary fibrosis. It enhances the bioavailability of key compounds and dually inhibits Wnt/β‐catenin and TGF‐β1/Smad pathways, presenting a potent therapeutic strategy.
Zhou Y +7 more
europepmc +2 more sources
Mineral Composition, Physicochemical Characteristics, and Antioxidant and Antibacterial Properties of Oil Extracted From Moroccan Bitter Apricot Kernels. [PDF]
Scientifica (Cairo)Apricot kernels, often regarded as by‐products, are a valuable source of oils and bioactive compounds such as polyphenols, which have applications in pharmacology, the food industry, and cosmetology. This study aimed to address the research gaps regarding the nutritional and functional potential of Moroccan bitter apricot kernels (BAKs) by analyzing ...
El Hajjaji MA +4 more
europepmc +2 more sources
Taohong Siwu Decoction Regulates MSC-Mediated H-Type Angiogenesis to Accelerate Bone Fracture Healing Through VHL/HIF-1α Ubiquitination. [PDF]
Mediators InflammBackground Bone fracture healing is a multifaceted process that involves different stages and intercellular interactions. In this study, we aimed to investigate the effect of Taohong Siwu decoction (TSD) on bone fracture healing and the underlying mechanisms.
Li W +8 more
europepmc +2 more sources
Evaluation of the effective dose of amygdalin for the improvement of antioxidant gene expression and suppression of oxidative damage in mice [PDF]
PeerJ, 2020 Background Little is known regarding the toxic and therapeutic doses of amygdalin. Treatment regimens and schedules can vary between humans and animal models, and there have been reports of cyanide toxicity due to amygdalin use. Objective The aim of this
Sarah Albogami +6 more
doaj +2 more sources
Insects, 2022 Grapholita molesta (Busck) (Lepidoptera: Tortricidae), Oriental fruit moth (OFM), attacks fruits and shoots of the economically important trees in Rosaceae.
Yi Wang +6 more
doaj +1 more source
Fmoc-amino acid-based hydrogel vehicle for delivery of amygdalin to perform neuroprotection
Smart Materials in Medicine, 2021 Amygdalin is widely distributed in the plant kingdom. Oral delivery of amygdalin releases hydrogen cyanide upon endogenous enzymes causing potential toxic effects to humans.
Zhao-yu Yang +13 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2022 Mounting evidence supports that long-term exposure to fine particle pollutants (PM2.5) is closely implicated in cardiovascular diseases, especially atherosclerosis.
Wang Bixu +6 more
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Amygdalin influences bladder cancer cell adhesion and invasion in vitro. [PDF]
PLoS ONE, 2014 The cyanogenic diglucoside amygdalin, derived from Rosaceae kernels, is employed by many patients as an alternative anti-cancer treatment. However, whether amygdalin indeed acts as an anti-tumor agent is not clear.
Jasmina Makarević +8 more
doaj +1 more source
Harnessing Hydrogen Cyanide (HCN): Responsive Chemical Tools for Delivering an Emerging Gasotransmitter. [PDF]
Angew Chem Int Ed EnglHCN is an important biological mediator, joining NO, CO, and H2S as a regulatory gasotransmitter. This report outlines the design, development, and application of responsive, activatable, and tunable HCN donors. In‐solution kinetics and selectivity data, as well as demonstration of HCN delivery in live cell environments, support the effectiveness of ...
Pluth MD.
europepmc +3 more sources
Amygdalin isolated from Amygdalus mongolica protects against hepatic fibrosis in rats
Acta Pharmaceutica, 2021 The aim of this research was to investigate the effect of amygdalin on hepatic fibrosis in rats. Amygdalin was purified and identified from the seeds of Amygdalus mongo lica.
Wang Jia +5 more
doaj +1 more source