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Alpha‐amylase as molecular target for treatment of diabetes mellitus: A comprehensive review

Chemical Biology and Drug Design, 2021
The alpha (α)‐amylase is a calcium metalloenzyme that aids digestion by breaking down polysaccharide molecules into smaller ones such as glucose and maltose. In addition, the enzyme causes postprandial hyperglycaemia and blood glucose levels to rise.
N. Kaur   +5 more
semanticscholar   +1 more source

Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

Critical reviews in food science and nutrition, 2021
Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α-glucosidase inhibitors have been shown to slow the release of glucose from starch and ...
C. Proença   +3 more
semanticscholar   +1 more source

Gravimetric determination of amylase-treated neutral detergent fiber in feeds with refluxing in beakers or crucibles: collaborative study.

Journal of AOAC International, 2002
As an important constituent of animal feeds, fiber represents the portion of feeds that is bulky and difficult to digest. The neutral detergent fiber (NDF) method, developed over 30 years ago, is the method of choice for measuring total fiber in forages ...
David R Mertens
semanticscholar   +1 more source

An insight of Alpha-amylase inhibitors as a Valuable Tool in the Management of Type 2 Diabetes Mellitus.

Current Diabetes Reviews, 2020
BACKGROUND Among the millions of people around the world, the most prevalent metabolic disorder is diabetes mellitus. Due to the drawbacks which are associated with commercially available antidiabetic agents new therapeutic approaches are needed to be ...
Roqia Bashary   +6 more
semanticscholar   +1 more source

Molecular dynamics simulation for screening phytochemicals as α-amylase inhibitors from medicinal plants

Journal of Biomolecular Structure and Dynamics, 2020
Diabetes mellitus (DM) is a complicated metabolic disorder with several enzymes, including α-amylase and α-glycosidase. The α-amylase is responsible for postprandial glucose levels; therefore, inhibiting its activity is helpful in diabetes management ...
Priyanka Sharma   +4 more
semanticscholar   +1 more source

Amylase

Emergency Medicine Clinics of North America, 1986
The laboratory determination of serum and urine amylase activity is commonly requested by the Emergency physician. While depressed levels are occasionally seen, they are almost always secondary to chronic pancreatitis and pancreatic destruction.
openaire   +2 more sources

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