Results 241 to 250 of about 197,077 (309)

An insight of Alpha-amylase inhibitors as a Valuable Tool in the Management of Type 2 Diabetes Mellitus.

Current Diabetes Reviews, 2020
BACKGROUND Among the millions of people around the world, the most prevalent metabolic disorder is diabetes mellitus. Due to the drawbacks which are associated with commercially available antidiabetic agents new therapeutic approaches are needed to be ...
Roqia Bashary, Manish Vyas, S. Nayak, A. Suttee, S. Verma, R. Narang, Gopal L. Khatik   +6 more
semanticscholar   +1 more source

Hydroxyapatite-decorated ZrO2 for α-amylase immobilization: Toward the enhancement of enzyme stability and reusability.

International Journal of Biological Macromolecules, 2020
Herein, the immobilization of α-amylase onto hydroxyapatite (HA) and hydroxyapatite-decorated ZrO2 (10%wt) (HA-ZrO2) nanocomposite were investigated. The immobilization yield was 69.7% and 84% respectively.
Yaaser Q. Almulaiky, N. M. Khalil, R. El-Shishtawy, T. Altalhi, Yousif Algamal, Musab M. Aldhahri, Sami A. Al-Harbi, Esam S. Allehyani, M. Bilal, M. M. Mohammed   +9 more
semanticscholar   +1 more source

Inhibition of α-amylase by flavonoids: Structure activity relationship (SAR).

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2019
Flavonoids are recognized to regulate animals' food digestion processes trough interaction with digestive enzymes. The binding capacity of hesperetin (HES), luteolin (LUT), quercetin (QUE), catechin (CAT) and rutin (RUT) with pancreatic α-amylase were ...
Alejandra I Martinez-Gonzalez, Á. G. Díaz-Sánchez, L. Rosa, Ismael Bustos-Jaimes, E. Álvarez-Parrilla   +4 more
semanticscholar   +1 more source

In vitro and in silico inhibition properties of fucoidan against α-amylase and α-D-glucosidase with relevance to type 2 diabetes mellitus.

Carbohydrate Polymers, 2019
This study investigated the in vitro and in silico inhibitory properties of fucoidan extracted from Turbinaria conoides against α-amylase and α-D-glucosidase.
Lakshmana Senthil S, C. Raghu, Arjun H A, Anantharaman P   +3 more
semanticscholar   +1 more source

C-glucosidic ellagitannins and galloylated glucoses as potential functional food ingredients with anti-diabetic properties: a study of α-glucosidase and α-amylase inhibition.

Food Chemistry, 2019
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, which can be counteracted by inhibition of α-glucosidase and α-amylase, both involved in the carbohydrate metabolism.
N. Cardullo, V. Muccilli, L. Pulvirenti, Anaëlle Cornu, L. Pouységu, D. Deffieux, S. Quideau, C. Tringali   +7 more
semanticscholar   +1 more source

BIG AMYLASE, LITTLE AMYLASE, AND URINARY AMYLASE

The Lancet, 1973
A R, Henderson, C W, Imrie, J, King
  +7 more sources

[Amylase].

Rinsho byori. The Japanese journal of clinical pathology, 2002
alpha-Amylase in human serum consists of at least two isozymes originating from either the pancreas or salivary glands. These isozymes can be determined by three methods, electrophoresis, inhibitor method and antibody method. The committee on enzymes of the International Federation of Clinical Chemistry recommended the approved method for the catalytic
Z, Ogawa, A, Hasegawa
openaire   +1 more source

Antidiabetic properties of dietary phenolic compounds: Inhibition effects on α‐amylase, aldose reductase, and α‐glycosidase

Biotechnology and applied biochemistry, 2019
Aldose reductase (AR), α‐amylase, and α‐glycosidase are vital enzymes to prevent diabetic complications. Here, AR was purified from sheep kidney using elementary methods with 111.11‐purification fold and with 0.85% purification yield.
Yeliz Demir, Lokman Durmaz, Parham Taslimi, I. Gulcin   +3 more
semanticscholar   +1 more source

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes.

International Journal of Biological Macromolecules, 2018
The glutathione S-transferase (GST) was purified from fresh blood erythrocytes using affinity column chromatography. Also, α-amylase from porcine pancreas and α-glycosidase from Saccharomyces cerevisiae were used as target enzymes.
I. Gulcin, Parham Taslimi, A. Aygün, Nastaran Sadeghian, Enes Bastem, O. I. Kufrevioglu, Fikret Turkan, F. Sen   +7 more
semanticscholar   +1 more source

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia.

International Journal of Biological Macromolecules, 2018
Diabetes mellitus (DM) is a chronic metabolic disease in which there are high blood sugar levels over a prolonged period. Aldose reductase (AR) belongs to aldo-keto reductase superfamily and plays a key role in the polyol pathway.
Parham Taslimi, Hatice Esra Aslan, Yeliz Demir, Necla Oztaskin, A. Maraş, I. Gulcin, Ş. Beydemir, S. Goksu   +7 more
semanticscholar   +1 more source