Results 251 to 260 of about 53,623 (345)

Efficacy and safety of once‐weekly semaglutide 2.4 mg for weight management in participants from China: A prespecified analysis of the STEP 7 randomized clinical trial

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2540-2551, May 2025.
Abstract Aim To evaluate the efficacy and safety of semaglutide 2.4 mg versus placebo for weight management in a population of Chinese adults with overweight or obesity. Materials and Methods In STEP 7 (NCT04251156), a double‐blind, phase 3a trial, adults from a predominantly East Asian population with overweight or obesity, with or without type 2 ...
Weijun Gu   +7 more
wiley   +1 more source

Fotagliptin add‐on therapy to metformin in patients with uncontrolled type 2 diabetes: A randomised, multicentre, double‐blind, placebo‐controlled, phase 3 trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Fotagliptin is a novel dipeptidyl peptidase‐4 inhibitor for glycaemic control in patients with type 2 diabetes (T2D). This trial aimed to assess the efficacy and safety of fotagliptin add‐on to metformin in patients with T2D. Materials and Methods In this phase 3 randomised, double‐blind, placebo‐controlled study, patients with T2D who had
Nan Yu   +13 more
wiley   +1 more source

Cell-free biosensor with automated acoustic liquid handling for rapid and scalable characterization of cellobiohydrolases on microcrystalline cellulose. [PDF]

open access: yesSynth Biol (Oxf)
Kim T   +13 more
europepmc   +1 more source

Transcriptional response in larvae of the generalist fruit fly Anastrepha obliqua feeding on three different tropical host plants

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated the molecular basis of host switching by the phytophagous West Indian fruit fly (A. obliqua). Third‐instar larvae showed differential gene expression according to host plants: red mombin, mango, and carambola. The main gene categories differentially expressed were digestion, detoxification, and gene regulators.
Sandra M. Velasco‐Cuervo   +5 more
wiley   +1 more source

Exploring a novel GH13_5 α-amylase from Jeotgalibacillus malaysiensis D5T for raw starch hydrolysis. [PDF]

open access: yesAMB Express
Radzlin N   +5 more
europepmc   +1 more source

Diagnostic approach to chronic diarrhoea in adult horses

open access: yesEquine Veterinary Education, Volume 37, Issue 6, Page 328-336, June 2025.
Summary Chronic diarrhoea presents a diagnostic challenge for both human physicians and equine veterinarians. There is currently no consensus in the equine veterinary literature on the definition of chronic diarrhoea. The differential list is extensive and identifying diarrhoea by pathophysiologic mechanism can help remove less likely diagnoses ...
E. Sjolin, A. Lack, L. G. Arroyo
wiley   +1 more source

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