Results 91 to 100 of about 4,821 (183)

Methods in the treatment of obesity [PDF]

, 2000
L'obesitat és una malaltia molt estesa que limita l'activitat i escurça la vida, i que es pot definir com un emmagatzemament patològic de reserves de greix.
Alemany i Lamana, Marià, Fernández López, José Antonio, Remesar, Xavier   +2 more
core  

Potential for clinical pancreatic islet xenotransplantation [PDF]

, 2014
Diabetes mellitus is increasing worldwide. Type 1 diabetes can be treated successfully by islet allotransplantation, the results of which are steadily improving.
Bottino, R, Cooper, DKC, Hara, H, Nagaraju, S, Satyananda, V, Trucco, M, Wijkstrom, M   +6 more
core   +1 more source

Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis.

PLoS ONE
The nuclear farnesoid X receptor (FXR), a master regulator of bile acid and metabolic homeostasis, is a key target for treatment of nonalcoholic steatohepatitis (NASH).
Luciano Adorini, Kristoffer Rigbolt, Michael Feigh, Jonathan Roth, Mary Erickson   +4 more
doaj   +1 more source

Metabolic effects of muraglitazar in type 2 diabetic subjects [PDF]

AIM: To assess the effect of muraglitazar, a dual peroxisome proliferator-activated receptor (PPAR)gamma-alpha agonist, versus placebo on metabolic parameters and body composition in subjects with type 2 diabetes mellitus (T2DM).
Casolaro, Arturo, Cersosimo, Eugenio, Defronzo, Ralph A., Fernandez, Marianella, Ferrannini, Ele, Gastaldelli, Amalia, Hardies, Jeane, Musi, Nicholas, Petz, Roberta, Tantiwong, Punting, Triplitt, Curtis   +10 more
core  

Management of diabetes across the course of disease: minimizing obesity-associated complications

Diabetes, Metabolic Syndrome and Obesity, 2011
Caroline M ApovianMedicine and Pediatrics, Boston University School of Medicine; Nutrition and Weight Management Center; and Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston Medical Center, Boston, MA, USAAbstract: Obesity
Apovian CM
doaj  

The combination of a glucagon-like peptide-1 and amylin receptor agonists reduces alcohol consumption in both male and female rats

Acta Neuropsychiatrica
Abstract Objective: Combining different pharmaceuticals may be beneficial when treating disorders with complex neurobiology, including alcohol use disorder (AUD). The gut-brain peptides amylin and GLP-1 may be of potential interest as they individually reduce alcohol intake in rodents.
Cajsa Aranäs, Christian E. Edvardsson, Lindsay Zentveld, Daniel Vallöf, Sarah Witley, Maximilian Tufvesson-Alm, Olesya T. Shevchouk, Jesper Vestlund, Elisabet Jerlhag   +8 more
openaire   +2 more sources

Neuroendocrine control of satiation [PDF]

, 2017
Eating is a simple behavior with complex functions. The unconscious neuroendocrine process that stops eating and brings a meal to its end is called satiation. Energy homeostasis is mediated accomplished through the control of meal size via satiation.
Asarian, Lori, Bächler, Thomas
core  

Targeting a metabolic OA in vivo model by a novel dual amylin calcitonin receptor agonist, KBP-056 [PDF]

Osteoarthritis and Cartilage, 2016
Reker, D., Hjuler, S., Gydesen, S., Andreasen, K., Karsdal, M., Bay-Jensen, A., Henriksen, K.   +6 more
openaire   +1 more source

Brain Amylin Signaling, Feeding, and Reward. [PDF]

Compr Physiol
Mietlicki-Baase EG.
europepmc   +1 more source

Obesity pharmacotherapy reimagined: The era of multi-receptor agonists and next-generation metabolic modulators, perspectives and controversies. [PDF]

Metabol Open
Lempesis IG, Dalamaga M.
europepmc   +1 more source