Results 61 to 70 of about 10,843,123 (260)

Multimodal Imaging Findings of Cerebral Amyloid Angiopathy Related Inflammation With Unusual Clinical Manifestation: A Case Report [PDF]

, 2023
Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare encephalopathy characterized by the coexistence of a perivascular inflammatory reaction in patients with cerebral amyloid angiopathy.
서상현, 유영훈, 이재훈, 주비오, 유한수, 안성준, 박미나   +6 more
core   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Structural MRI [PDF]

, 2011
Clinical neuroimaging is increasingly being used in the diagnosis of neurodegenerative diseases and has become one of the most important paraclinical tools in the diagnosis of dementia.
Wattjes, M.P., Mike P. Wattjes
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Diagnosis, pathomechanisms and therapy of cerebral amyloid angiopathy-related inflammation (CAA-ri)

Neurological Research and Practice
Background Research of the past years has refined our perception of cerebral amyloid angiopathy-related inflammation (CAA-ri) as a subacute autoimmune encephalopathy, which is presumably caused by elevated CSF concentrations of anti-amyloid β (Aβ ...
Rebecca M. Seifert, Randolf Klingebiel, Wolf-Rüdiger Schäbitz   +2 more
doaj   +1 more source

Inflammatory components in human Alzheimer's disease and after active amyloid-β42 immunization

, 2013
Inflammatory processes are important in the pathogenesis of Alzheimer's disease and in response to amyloid-β immunotherapy. We investigated the expression of multiple inflammatory markers in the brains of 28 non-immunized patients with Alzheimer's ...
Cheaveau, M., Morgan, William, Cheaveau, Matthew, Boche, Delphine, Bharambe, V., Holmes, C., Love, S., Nicoll, James A R, Harris, Scott, Bharambe, Viraj, Neal, James W, Love, Seth, Nicoll, J.A.R., Zotova, E., Boche, D., Morgan, W., Neal, J.W., Holmes, Clive, Zotova, Elina   +18 more
core   +1 more source

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey [PDF]

, 2014
We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI).
Erikdotter, M, Samantha Galluzzi, Peters, Oliver, Galluzi, S, Andreas Monsch, Jones, Roy W, Mehrabian, S., Zekry, Dina, Wilcock, G, Sarazin, M., Sánchez-Castellano, Carmen, Martinez-Lage, P, Kehoe, P.G., Wallin, Åsa,, Hallikainen, M., Monsch, A, Santana, I, Felician, O, Frolich, L, Rikkert, M.O., Isabel Santana, Wilcock, Gordon, Jean‐Marc Orgogozo, Flavio Nobili, Mecocci, P, Hausner, Lucrezia, Roy W. Jones, Jessen, F., Heuser, I., Isabell Heuser, Eric Salmon, David Wilkinson, Froelich, L., Félician, Olivier, Maria Eriksdotter, Ceccaldi, M, Sarazin, M, Olde Rikkert, Marcel, de Mendonca, A., Aguera, E., Galluzzi, Samantha, Felician, O., Pasquier, F., Patrick Gavin Kehoe, Wolf, H, Nordberg, Agneta, Shima Mehrabian, Latchezar Traykov, Frolich, L., Mira Didic, Dartigues, Jean François, Hasselbalch, S.G., Aguera, Eduardo, Alberto Lleo, Sarazin, Marie, Martina Bocchetta, Brian Lawlor, Wallin, Åsa K, Dartigues, J.F., Monsch, A., Magda Tsolaki, Wilkinson, D., Giovanni B. Frisoni, Sanchez-Castellano, C, Yener, Goersev, NOBILI, FLAVIO MARIANO, Nobili, Flavio, Eriksdotter, Maria, Bernabei, R, Hallikainen, M, Gertz, H.J., Frisoni, Giovanni B., Lleo, A, Eduardo Aguera, Hallikainen, Merja, Roberto Bernabei, Alexandre de Mendonça, Gordon Wilcock, Visser, Pieter Jelle, Bullock, R., Frisoni, G.B., Bernabei, Roberto, Jones, Roy W., Alexander Kurz, Sanchez-Castellano, C., Wallin, Åsa, Bochetta, M, Bullock, R, Martinez-Lage, P., Patrizia Mecocci, Frank Jessen, Lleo, Alberto, Ceccaldi, M., Pablo Martinez‐Lage, Nobili, F., Florence Pasquier, Salmon, E., Eriksdotter, M., Lawlor, B., de Mendonça, Alexandre, Dartigues, Jean-François, Jessen, F, Pasquier, Florence, Marie Sarazin, Lucrezia Hausner, Monsch, Andreas, Rikkert, Marcel Olde, Dina Zekry, Carmen Sánchez‐Castellano, Pasquier, F, Traykov, L., Didic, M., Tsolaki, M, Nordberg, A., Pieter Jelle Visser, Kehoe, Patrick Gavin, Orgogozo, J.M., Froelich, Lutz, Kurz, A, Nobili, F, Bocchetta, M., Lund University., Martinez-Lage, Pablo, Agneta Nordberg, Åsa K. Wallin, Frisoni, G. B., Hasselbalch, Steen G, Zekry, D., Wilkinson, D, Gertz, Hermann Josef, Ceccaldi, Mathieu, Galluzzi, S., Santana, Isabel, Wilcock, G., Lleo, A., Mehrabian, S, Kurz, A., Heuser, Isabell, Gertz, Hermann-Josef, Kurz, Alexander, Wilkinson, David, Jean‐François Dartigues, Oliver Peters, Hausner, L, Mecocci, Patrizia, Peters, O., Roger Bullock, Lutz Frölich, Frisoni, Giovanni B, Merja Hallikainen, Orgogozo, Jean Marc, Jones, R.W., Henrike Wolf, Nordberg, A, Mecocci, P., Olde Rikkert, M, Olivier Félician, Wolf, Henrike, Bullock, Roger, Yener, G, Wallin, Åsa K., Peters, O, Yener, Görsev, Wolf, H., Didic, Mira, Mathieu Ceccaldi, Hausner, L., de Mendonca, A, Lawlor, Brian, Jessen, Frank, Orgogozo, Jean-Marc, Bernabei, R., Marcel Olde Rikkert, Mendonca, A. de, Heuser, I, Mehrabian, Shima, Salmon, Eric, Traykov, L, Visser, P.J., Bocchetta, Martina, Aguera, E, Martinez Lage, Pablo, Frölich, Lutz, Hermann‐Josef Gertz, Steen G. Hasselbalch, Didic, M, Tsolaki, M., Tsolaki, Magda, Hasselbalch, Steen G., Santana, I., Hasselbach, S.G., Lawlor, B, Olde Rikkert, M.G.M., Yener, G., Görsev Yener, Wallin, A.K., Traykov, Latchezar, Sänchez Castellano, Carmen   +197 more
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White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source