Results 111 to 120 of about 466,481 (267)

Genetic Targeting Aromatase in Male Amyloid Precursor Protein Transgenic Mice Down-Regulates β-Secretase (BACE1) and Prevents Alzheimer-Like Pathology and Cognitive Impairment [PDF]

, 2010
Carrie McAllister, Jiangang Long, Adrienne Bowers, Aaron Walker, Philip Cao, Shin-Ichiro Honda, Nobuhiro Harada, Matthias Staufenbiel, Yong Shen, Rena Li   +9 more
openalex   +1 more source

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

An Unusual Cause of Intestinal Ulcers Masquerading as Inflammatory Bowel Disease: A Case Report of Allied Disorders of Hirschsprung’s Disease

Journal of Inflammation Research
Minli Hu,1,* Hao Fang,2,* Yibing Hu,1 Chong Lu,1 Yuan Chen,1 Zhifeng Zhong,3 Hongqi Shi,4 Qunying Wang1 1Department of Gastroenterology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, People’s Republic of China; 2Department of Traumatology,
Hu M, Fang H, Hu Y, Lu C, Chen Y, Zhong Z, Shi H, Wang Q   +7 more
doaj  

Spontaneous cerebral amyloid angiopathy‐related intracerebral hemorrhages in aged capuchin monkey [PDF]

Roberta Rodriguez, Maria da Graça Morais Martin, Sônia Maria Dozzi Brucki, Maria Concepción Gracía Otaduy, Leonel Tadao Takada, Lea T. Grinberg, Jessica Mendes de Souza, Cláudia Kimie Suemoto, Claudia da Costa Leite, Carlos Tomaz, Maria Clotilde Henriques Tavares, Ricardo Nitrini   +11 more
openalex   +1 more source

Use of Zebrafish Genetic Models to Study Etiology of the Amyloid-Betaand Neurofibrillary Tangle Pathways in Alzheimer's Disease

, 2021
Jennifer L. Freeman, Keturah Kiper
openalex   +2 more sources

Peptide Sequence Programmed Piezoelectric Response by Supramolecular Self‐Assembly

Advanced Science, EarlyView.
In this study, hydrophobic tripeptides are explored as building blocks for stable piezoelectric crystals. Tripeptides with phenylalanine at the central position self‐assembled into uniform, thermally stable crystals. Piezoresponse force microscopy reveals a high effective piezoelectric coefficient of 24.0 pC N−1, attributed to asymmetric molecular ...
Xuejiao Yang, Shuaijie Liu, Honglei Lu, Yuehui Wang, Hongyue Zhang, Wei Ji, Huaimin Wang   +6 more
wiley   +1 more source

Humanin attenuates Alzheimer-like cognitive deficits and pathological changes induced by amyloid β-peptide in rats [PDF]

, 2014
Gaoshang Chai, Dong-Xiao Duan, Rong-Hong Ma, Jianying Shen, Honglian Li, Zhiwei Ma, Yu Luo, Lu Wang, Xinhua Qi, Qun Wang, Jian‐Zhi Wang, Zelan Wei, Darrell D. Mousseau, Li Wang, Gong‐Ping Liu   +14 more
openalex   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Limited utility of Mayo 2012 cardiac staging system for risk stratification of patients with advanced cardiac AL amyloidosis - analysis of a uniformly treated cohort of 1,275 patients

Haematologica
Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Cohen, Darren Foard, Ana Martinez-Naharro, Lucia Venneri, Marianna Fontana, Philip N. Hawkins, Julian Gillmore, Helen J. Lachmann, Shameem Mahmood, Carol Whelan, Amy A. Kirkwood, Ashutosh Wechalekar   +14 more
doaj   +1 more source

Hypochlorite-induced oxidation promotes aggregation and reduces toxicity of amyloid beta 1-42

, 2023
Noralyn B. Mañucat‐Tan, Ashfaq Chowdhury, Rodrigo Cataldi, Rafaa Zeineddine Abdullah, Janet R. Kumita, Amy R. Wyatt   +5 more
openalex   +1 more source