Results 251 to 260 of about 516,976 (376)

Amyloid-reoriented enzyme catalysis. [PDF]

Nat Commun
Sawazaki T, Murai F, Yamamoto K, Sasaki D, Sohma Y.   +4 more
europepmc   +1 more source

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

Animal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang, Yi Sun, Chunsheng Yang, Nan Zhang   +3 more
wiley   +1 more source

Advancements in the treatment of Alzheimer's disease: a comprehensive review. [PDF]

Dement Neuropsychol
Rajanna S, Gundale PP, Dev Mahadevaiah A.   +2 more
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Emerging biophysical origins and pathogenic implications of amyloid oligomers. [PDF]

Nat Commun
Tang H, Andrikopoulos N, Li Y, Ke S, Sun Y, Ding F, Ke PC.   +6 more
europepmc   +1 more source

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei, Chunhua Liu, Jianyu Chen, Yuxiao Yao, Dajiang Qin   +4 more
wiley   +1 more source

Lecanemab approval in EU: what should we be ready for?- the EANM perspective. [PDF]

Eur J Nucl Med Mol Imaging
Yakushev I, Verger A, Brendel M, Cecchin D, Fernandez PA, Fraioli F, Grimmer T, Tolboom N, Traub-Weidinger T, Guedj E, Van Weehaeghe D.   +10 more
europepmc   +1 more source

Structural studies of a carbohydrate-containing immunoglobulin-λ-light-chain amyloid-fibril protein (AL) of variable subgroup III [PDF]

, 1986
E. Holm, Knut Sletten, Gunnar Husby
openalex   +1 more source

Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology

Annals of Neurology, EarlyView.
Objective Some individuals demonstrate greater cognitive resilience—the ability to maintain cognitive performance despite adverse brain‐related changes—through as yet unknown mechanisms. We examined whether cortical thickness in several brain regions confers resilience against cognitive decline in amyloid‐positive adults by moderating the effects of ...
McKenna E. Williams, Christine Fennema‐Notestine, Tyler R. Bell, Shu‐Ju Lin, Stephen J. Glatt, William S. Kremen, Jeremy A. Elman, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

Adenomatoid odontogenic tumor.Ultrastructural demonstration of two cell types and amyloid

, 1979
Robert R. Smith, Jean L. Olson, Grover M. Hutchins, William A. Crawley, L. Stefan Levin   +4 more
openalex   +1 more source