Results 151 to 160 of about 45,801 (303)

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

P2‐130: Beta‐amyloid peptide 1‐42 binds to N‐terminal fragment of cytochrome C oxidase subunit 1 (COX1) [PDF]

, 2012
Luis Hernández, José Luna‐Muñoz, Gonzalo Acero, Ricardo Vázquez‐Ramírez, Goar Gevorkian   +4 more
openalex   +1 more source

Cu(I) Is a Game Changer in the Arrest of Cu(Aβ)‐Induced ROS Production in the Presence of Competing Zn(II) Ions

Chemistry – A European Journal, EarlyView.
ABSTRACT ROS production due to Cu(amyloid‐β) redox cycling is proposed to contribute to the oxidative stress observed in Alzheimer's disease brains. We previously reported on a nitrogen and sulfur‐containing ligand, L, able to arrest Cu(Aβ)‐induced ROS production [Chem. Eur. J. 2023, 29,].
Marielle Drommi, Kyangwi Patrick Malikidogo, Elena Atrián‐Blasco, Charlène Esmieu, Christelle Hureau   +4 more
wiley   +1 more source

Xanthene Food Dye, as a Modulator of Alzheimer's Disease Amyloid-beta Peptide Aggregation and the Associated Impaired Neuronal Cell Function

, 2011
H. Edward Wong, Inchan Kwon
openalex   +2 more sources

Liraglutide improves cognitive function by reducing amyloid-beta peptide accumulation and inhibiting inflammation in 5×FAD mice [PDF]

, 2021
Liqin Qi, Lijing Lin, Jiaping Zheng, Xiaoying Liu, Xiaohong Liu, Zhou Chen, Libin Liu   +6 more
openalex   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, EarlyView.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins [PDF]

, 2017
Agosta, Alata, Albert A. Davis, Aleshkov, Allen, Alzheimer, Anderson, Atagi, Bailey, Bales, Bales, Bales, Basak, Bateman, Beffert, Beffert, Beffert, Bell, Bell, Benilova, Benjamin, Bernardi, Bertram, Bien-Ly, Bien-Ly, Biere, Brecht, Brunden, Bu, Caselli, Castellano, Castellano, Cedazo-Mínguez, Cheng, Cirrito, Cirrito, Cole, Cooper, Corder, Corder, Cotman, David M. Holtzman, de la Torre, Deane, Deane, DeMattos, Drory, Emamzadeh, Engelborghs, Esparza, Evans, Fabre, Fagan, Fagan, Farrer, Fryer, Fryer, Funato, Gallardo, Gallyas, Games, Gao, Garai, Govone, Greenberg, Grehan, Guerreiro, Gustafson, Halliday, Hardy, Harris, Harris, Heinonen, Hirsch-Reinshagen, Hirsch-Reinshagen, Holtzman, Holtzman, Holtzman, Holtzman, Hone, Hong, Hu, Huang, Huang, Huang, Hughes, Irizarry, Irwin, Irwin, Irwin, Iwai, Jakes, Jarrett, Jason D. Ulrich, Jellinger, Ji, Jiang, Jonsson, Josephs, Kanekiyo, Kehoe, Kim, Kim, Kim, Klunk, Klunk, Koistinaho, Koldamova, Korczyn, Kotzbauer, Lacomblez, LaDu, LaDu, Lashuel, Lee, Li, Li, Li, Li, Liao, Lill, Lippa, Liu, Liu, Ma, Mahley, Mahley, Mak, Mandrekar, Marchesi, Marder, Martin, Masliah, Mathis, Mattila, Mauch, McKee, Mikolaenko, Morris, Mui, Nalivaeva, Namba, Narita, Nathan, Nelson, Nielsen, Ohm, Panegyres, Paresce, Paresce, Pfeifer, Pfrieger, Pitas, Poirier, Praline, Rebeck, Rebeck, Reiman, Riemenschneider, Rockenstein, Roses, Roychaudhuri, Saavedra, Sabbagh, Saito, Sanan, Schmechel, Shaffer, Shibata, Siderowf, Srinivasan, Strittmatter, Strittmatter, Strittmatter, Sullivan, Sunderland, Szaruga, Tamamizu-Kato, Tesseur, Thal, Theendakara, Tien-Phat V. Huynh, Tiraboschi, Tokuda, Tsuang, Ulrich, Van Gool, van Horssen, Verghese, Wahrle, Wahrle, Wakabayashi, Wang, Watanabe, Wilson, Wisniewski, Wisniewski, Withers, Wood, Wyss-Coray, Yang, Ye, Yeh, Yuan, Zerbinatti, Zhang, Zhang, Zlokovic   +207 more
core   +2 more sources

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

Clinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz, Eric Farber‐Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J. Garrett, Samuel M. Rubinstein, Michael G. Fradley, Mohammed E. Alomar, Danny DeAvila, Kenneth H Shain, R. Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C. Baz, Yan Gong   +15 more
wiley   +1 more source

On the Role of Platelet-Generated Amyloid Beta Peptides in Certain Amyloidosis Health Complications [PDF]

, 2020
Mikhail Inyushin, Astrid Zayas‐Santiago, Legier V. Rojas, Lilia Kucheryavykh   +3 more
openalex   +1 more source