Results 151 to 160 of about 86,530 (342)

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

open access: yesAnimal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao   +12 more
wiley   +1 more source

Framework for assessing the risk to a field from fraudulent researchers: A case study of Alzheimer's disease

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Concerns over research integrity are rising, with increasing attention to potential threats from untrustworthy authors. We established a framework to gauge the potential negative influence of researchers potentially engaged in misconduct. The field of Alzheimer's disease (AD) research has been a focal point of these worries. This study aims to
Chaoqun Ni, B. Ian Hutchins
wiley   +1 more source

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

open access: yesBioEssays, EarlyView.
Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler   +2 more
wiley   +1 more source

A guide to selecting high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence [version 2; peer review: 2 approved, 1 approved with reservations]

open access: yesF1000Research
The amyloid-beta precursor protein is a transmembrane protein expressed in many tissues and highly concentrated in the brain. The protein is of significant interest due to its involvement in the generation of amyloidogenic β-amyloid peptides, prone to ...
Carl Laflamme   +4 more
doaj  

Mammalian Tolerance to Amino Acid Heterochirality

open access: yesChemBioChem, EarlyView.
Organisms preferentially use l‐amino acids (l‐AAs). However, de novo synthesized l‐AAs are in part converted to d‐AAs. The ribosome has a robust system to use l‐AAs for protein synthesis, whereas non‐ribosomal synthesis can also use d‐AAs. Furthermore, some AA residues can be post‐translationally isomerized through enzymatic or spontaneous processes ...
Sakiko Taniguchi   +4 more
wiley   +1 more source

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