ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer +25 more
wiley +1 more source
Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study [PDF]
, 2006 Aistė Jekabsone +4 more
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In vivo administration of D609 leads to protection of subsequently isolated gerbil brain mitochondria subjected to in vitro oxidative stress induced by amyloid beta-peptide and other oxidative stressors: Relevance to Alzheimer’s disease and other oxidative stress-related neurodegenerative disorders [PDF]
, 2006 Mubeen A. Ansari +6 more
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ESC Heart Failure, EarlyView.Abbreviations: TAVI, transcatheter aortic valve implantation; ATTR‐CM, transthyretin cardiac amyloidosis. We aimed to diagnose occult ATTR‐CM in patients with severe aortic stenosis undergoing TAVI using bone scintigraphy. We verified a diagnosis of ATTR‐CM in 8 of 171 (4.7 %) consecutive aortic stenosis patients who underwent TAVI.
Margrethe Flesvig Holt +15 more
wiley +1 more source
Overpressure Exposure From .50-Caliber Rifle Training Is Associated With Increased Amyloid Beta Peptides in Serum. [PDF]
Front Neurol, 2020 Thangavelu B +5 more
europepmc +1 more source
Protective effects of compound FLZ on beta-amyloid peptide-(25-35)-induced mouse hippocampal injury and learning and memory impairment1 [PDF]
, 2006 Fang Fang, Geng-Tao Liu
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ESC Heart Failure, EarlyView.Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem +13 more
wiley +1 more source
Microglia Do Not Take Up Soluble Amyloid-beta Peptides, But Partially Degrade Them by Secreting Insulin-degrading Enzyme. [PDF]
Neuroscience, 2020 Fu H, Liu B, Li L, Lemere CA.
europepmc +1 more source
P4–093: Sialylation enhances the secretion of neurotoxic amyloid–beta peptide: Regulatory role of BACE1 for APP sialylation [PDF]
, 2006 Yasuhiro Hashimoto +6 more
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