Results 251 to 260 of about 376,147 (348)

PET imaging of TREM2 in amyloid-beta induced neuroinflammation. [PDF]

open access: yesEur J Nucl Med Mol Imaging
Dahlén AD   +6 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

open access: yesBMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou   +6 more
wiley   +1 more source

Multifaceted Effects of a Multiple Nitric Oxide Photoreleaser and its Photoproducts on Amyloid‐β Aggregation

open access: yesChemBioChem, EarlyView.
A blue light‐activatable NO photodonor sequentially releases two NO molecules accompanied by two stable photoproducts, showing differentiated effects on the β‐amyloid aggregation. Aberrant aggregation of β‐amyloid (Aβ) peptides into insoluble fibrils is recognized as one of the hallmarks of Alzheimer's disease (AD).
Francesca Laneri   +2 more
wiley   +1 more source

Human amylin is a potent antimicrobial peptide that exhibits antimicrobial synergism with the amyloid beta protein. [PDF]

open access: yesAlzheimers Dement
Vijaya Kumar DK   +12 more
europepmc   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

open access: yesChemBioChem, EarlyView.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh   +7 more
wiley   +1 more source

Sequence‐Dependent Heterotypic Assemblies of Intrinsically Disordered Peptides

open access: yesChemistryEurope, EarlyView.
Two oppositely charged intrinsically disordered peptides (IDPs) coassemble into heterotypic nanofibers. Homochiral mixtures (L/L IDPs) form homogeneous, aligned bundles with the more positive IDP. Heterochiral mixtures (L/D IDPs) yield heterogeneous, twisted bundles as positive‐IDP content increases.
Yuchen Qiao   +4 more
wiley   +1 more source

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