Results 181 to 190 of about 82,488 (290)

Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD), which are characterized by the accumulation of misfolded protein aggregates and cognitive/motor dysfunction, are the most prevalent neurodegenerative diseases (NDDs). Despite strategic investigations aimed at augmenting the pharmaceutical pipeline, available drugs for AD and PD merely slow
Yoo Joo Jeong, Hyun‐ju Lee, Jun‐Su Kim, Seung‐Jae Kim, Unhui Jo, Jin Yeop Park, Su Jin Jun, Won Seok Lee, Mingoo Song, Donggii Kim, Gyoujin Cho, Jeong‐Heon Song, Hyang‐Sook Hoe   +12 more
wiley   +1 more source

Flavonoids and fibrate modulate apoE4-induced processing of amyloid precursor protein in neuroblastoma cells. [PDF]

Front Neurosci, 2023
Davra V, Benzeroual KE.
europepmc   +1 more source

Ligand-dependent G Protein Coupling Function of Amyloid Transmembrane Precursor [PDF]

, 1995
Takashi Okamoto, Shizu Takeda, Yoshitake Murayama, Etsuro Ogata, Ikuo Nishimoto   +4 more
openalex   +1 more source

Nano‐Biosensors for Continuous Cognitive and Stress Monitoring: Applications in Learning and Mental Well‐Being

Nano Select, EarlyView.
Nano‐biosensors offer real‐time monitoring of cognitive and emotional states through biomarkers like cortisol and dopamine. They enhance personalized learning, mental health interventions, and daily performance across sectors. Integrated into wearables and IoT, they promise a transformative impact while raising ethical, technological, and regulatory ...
Priscilla Adomako Gyasi, Jesse Nii Okai Amu‐Darko, Binghai Sun, Eliasu Issaka, Seth Yeboah Ntim, Michael Enyan, Shahid Hussain   +6 more
wiley   +1 more source

Brain derived neurotrophic factor and secreted amyloid precursor protein-α response to moderate and high intensity exercise. [PDF]

Physiol Rep
Spencer FSE, Elsworthy RJ, Breen L, Bishop JRB, Lucas SJE, Aldred S.   +5 more
europepmc   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Targeting amyloid precursor protein shuttling and processing - long before amyloid beta formation

Neural Regeneration Research, 2017
Sage Arbor
doaj   +1 more source

Amyloid precursor protein promotes MASH progression by upregulating death receptor 6-mediated hepatocyte apoptosis. [PDF]

J Biol Chem
Guo Y, Huang H, Yang L, Shen Q, Liu Z, Wang Q, Chen S, Pan J, Zhai H, Li Y, Xu L, Yu C, Xu C.   +12 more
europepmc   +1 more source

Cholesterol-dependent generation of a unique amyloid β-protein from apically missorted amyloid precursor protein in MDCK cells

, 1998
Tetsuya Mizuno, Christian Haass, Makoto Michikawa, Katsuhiko Yanagisawa   +3 more
openalex   +1 more source

Enhanced Release of Amyloid -Protein from Codon 670/671 Swedish Mutant -Amyloid Precursor Protein Occurs in Both Secretory and Endocytic Pathways [PDF]

, 1996
Ruth G. Perez, Sharon L. Squazzo, Edward H. Koo   +2 more
openalex   +1 more source