The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance [PDF]
Baiping Wang +6 more
openalex +1 more source
Redox environment modulates in vitro aggregation of Ataxin‐3, the protein implicated in spinocerebellar ataxia type 3. Reducing conditions stabilize native monomers and prevent aggregation, whereas oxidative conditions promote the formation of non‐native conformers and disulfide‐linked oligomers within the Josephin domain (JD).
Martyna Podlasiak +10 more
wiley +1 more source
Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein [PDF]
Sung Hee Baek +5 more
openalex +1 more source
ABSTRACT Background People with Down syndrome (DS) have a strong genetic predisposition to Alzheimer's disease (AD). However, the clinical burden and associated risk factors in diverse, non‐Western populations remain less understood. This study aimed to investigate the prevalence of dementia in Japanese adults with DS and to identify modifiable ...
Shintaro Takenoshita +6 more
wiley +1 more source
γ-Cleavage Is Dependent on ζ-Cleavage during the Proteolytic Processing of Amyloid Precursor Protein within Its Transmembrane Domain [PDF]
Guojun Zhao +6 more
openalex +1 more source
The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell +6 more
wiley +1 more source
A synapse perspective on the function of the amyloid precursor protein. [PDF]
Kruse P, Eichler A, Klukas L, Lenz M.
europepmc +1 more source
Amyloid precursor protein in human breast cancer: An androgen‐induced gene associated with cell proliferation [PDF]
Kiyoshi Takagi +9 more
openalex +1 more source
Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging [PDF]
Chen, Wei +8 more
core +2 more sources

