Results 271 to 280 of about 343,599 (390)

Long‐term amyloid PET and MRI outcomes in a menopausal hormone therapy trial

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Associations of short‐term use of menopausal hormone therapy (mHT) with Alzheimer's disease (AD) and structural magnetic resonance imaging (MRI) biomarkers were investigated 10 years after an mHT trial. METHODS Recently menopausal women with good cardiovascular health were randomized to oral conjugated equine estrogens (oCEE) or ...
Kejal Kantarci, Firat Kara, Nirubol Tosakulwong, Angela J. Fought, Christopher G. Schwarz, Matthew L. Senjem, June Kendall‐Thomas, Paul Min, Val J. Lowe, Clifford R. Jack, Ekta Kapoor, Julie A. Fields, Kent R. Bailey, Taryn T. James, Laura Faubion, Rogerio A. Lobo, JoAnn E. Manson, Lubna Pal, Dustin B. Hammers, Eliot A. Brinton, Michael Malek‐Ahmadi, Marcelle I. Cedars, Frederick N. Naftolin, Nanette Santoro, Virginia M. Miller, Sherman M. Harman, N. Maritza Dowling, Carey E. Gleason   +27 more
wiley   +1 more source

Identification of fibrinogen Aα-chain as an amyloid precursor protein in a case of canine coronary artery amyloidosis. [PDF]

J Vet Diagn Invest
Iwaide S, Wachoski-Dark GL, Murakami T, Sedghi Masoud N, Itoh Y, Hisada M, Kimura K, Shibahara T, Haritani M, Caswell JL.   +9 more
europepmc   +1 more source

Total Amyloid Precursor Protein Measurement [PDF]

, 2020
openaire   +1 more source

Sex‐specific acceleration of Alzheimer's pathogenesis by chronic sleep‐deprivation

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep impairments likely contribute to Alzheimer's pathology, though specific contributions to disease progression are incompletely understood. We propose that autophagic impairment is associated with chronic sleep disruption and examine how sleep loss and stress influence disease development, including having impacts on ...
Darcy Wear, Christopher Daniel Morrone, Dominic Simpson, Fang Liu, Syed Abid Hussaini, Wai Haung Yu   +5 more
wiley   +1 more source

Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop. [PDF]

Front Pharmacol
Petrushanko IY, Lisitskii DR, Filonov FA, Leonova OG, Mitkevich VA, Strelkova MA, Makarov AA.   +6 more
europepmc   +1 more source

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep–wake disturbances frequently occur at early stages of Alzheimer's disease (AD) and accelerate disease progression, but the underlying neural mechanisms are not fully understood. METHODS We examined sleep–wake behavior and locus coeruleus (LC) activity in young 5xFAD mice using electrophysiology and pharmacological approaches
Yi‐Ci Zhang, Xue‐Ting Zhang, Peng‐Yue Chen, Zi‐Yue Zhou, Mao‐Qing Huang, Kai‐Wen He   +5 more
wiley   +1 more source

Neuron-Astrocyte Interactions in Aging and Alzheimer's Disease: Dysregulation of Amyloid Precursor Protein. [PDF]

Ageing Longev
Jáuregui GV, Parpura V.
europepmc   +1 more source

ADAM10; amyloid precursor protein (APP) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source