Results 281 to 290 of about 82,488 (290)

The effect of corticosteroids on amyloid β precursor protein/amyloid precursor-like protein expression and processing in vivo

Neuroscience Letters, 1999
In this study, we have investigated the effect of altered corticosteroid levels on the expression and processing of the amyloid beta precursor protein (A betaPP) and its amyloid precursor-like protein (APLP) homologue in rat brain. Four groups of animals were used in the study: sham operated, adrenalectomised, and adrenalectomised treated with either ...
Kieran C. Breen, Christine M. Coughlan, Jonathan R. Seckl, Grant R. Budas   +3 more
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Genetics of the Alzheimer Amyloid Protein Precursor

1990
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by gradual loss of memory, reasoning, orientation, and judgment (Katzman, 1983). AD generally occurs as a sporadic disorder of unknown cause. However, a proportion of cases, which have been termed familial Alzheimer’s disease (FAD), are caused by a genetic defect that is
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Biological activities of amyloid precursor protein [PDF]

Acta Biologica Hungarica, 1998
Amyloid precursor protein (APP), a transmembrane glycoprotein, is the source of amyloidogenic β-amyloid peptide (βAP), the major constituent of the peptides deposited in senile plaques. Normallycleaved forms of APP exert potent neuroprotective action.
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Posttranslational Modifications of the Amyloid Precursor Protein: Glycosylation

2003
Many studies have demonstrated the importance of amyloid precurser protein (APP) in the pathogenesis of Alzheimer's disease. Nonetheless, the exact mechanism by which APP contributes to the pathogenesis of Alzheimer's disease is still not clear. Because APP is a glycoprotein, and because glycosylation can be important in the cell biology of individual ...
Magda Stwora-Wojczyk, Tomasz Rozmyslowicz, Boguslaw S. Wojczyk, Chen Liu, Steven L. Spitalnik   +4 more
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Signaling by β-Amyloid Precursor Protein

1998
The β-amyloid precursor protein (βAPP) is widely expressed in neurons and glial cells throughout the mammalian nervous system. APP is a large transmembrane glycoprotein having a single transmembrane domain, a large extracelluar N-terminus, and a short cytoplasmic C-terminus (Kang et al., 1987).
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Expression of amyloid precursor protein

Neurochemistry International, 1992
Henrik Gaardsvoll, Georgi Gegelashvili, Elisabeth Bock, Dorte Linnemann   +3 more
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Amyloid-beta Precursor Protein

RCSB Protein Data Bank, 2006
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Targeting amyloid precursor protein

Annals of Neurology, 2011
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Amyloid Precursor Protein

2007
S.J. Enna, David B. Bylund
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Glycosylation of Amyloid β Precursor Protein

2014
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