Results 111 to 120 of about 31,379 (232)

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy   +5 more
wiley   +1 more source

A Case of Systemic Amyloidosis Diagnosed After Excision of a Cutaneous Tumour of the Buttocks

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT A 72‐year‐old Japanese man was referred to our hospital with two tumours on the buttocks. Two solitary, 2.5 × 1.5 cm‐sized, dark brown, well‐demarcated elevated plaques were observed, one on each side of the gluteal cleft, and dermoscopic examination showed comedo‐like openings, multiple milia‐like cysts, and a cerebriform pattern with ...
Tomomichi Shimizu   +9 more
wiley   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

open access: yesMedicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani   +5 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

Localized Vocal Cord Amyloidosis [PDF]

open access: yes, 2007
Localized laryngeal amyloidosis is an uncommon diease with limited long-term follow-up studies. The precise etiology and pathogenesis are not entirely clear. We present a case of localized laryngeal amyloidosis.
Yazici, Ayten   +3 more
core   +1 more source

Ethnicity in systemic AL amyloidosis may impact risk stratification

open access: yesHaematologica
Not available.
Jahanzaib Khwaja   +12 more
doaj   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

Disease burden of ATTR amyloidosis based on the SF-36® health survey

open access: yesCardio-Oncology
Transthyretin (ATTR) amyloidosis is a progressive systemic disease associated with substantial morbidity and mortality. Although health-related quality of life (HRQoL) assessments are increasingly incorporated into clinical trials, data in ATTR ...
Vaishali Sanchorawala   +9 more
doaj   +1 more source

Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis

open access: yesPharmaceuticals
Background/Objectives: Antibody light chains form amyloid fibrils that lead to progressive tissue damage in amyloid light chain (AL) amyloidosis. The properties of each patient’s unique light chain appear to determine its propensity to form amyloid.
Gareth J. Morgan   +4 more
doaj   +1 more source

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