Results 121 to 130 of about 99,289 (260)

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Comparison of the HemoScreen Point‐Of‐Care Haematology Analyser With Sysmex XN, Beckman Coulter DxH 560 and HORIBA Yumizen H550 in Patients With Abnormal Blood Counts

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction HemoScreen is a portable point‐of‐care testing (POCT) haematology analyser capable of measuring 20 complete blood count (CBC) parameters, including a 5‐part leukocyte differential, from venous and capillary blood. This study compared selected CBC and white blood cell (WBC) differential parameters obtained using HemoScreen with ...
Katarína Hradská, Martin Pulcer, Michaela Skořupová, Tereza Popková, Michal Kaščák, Jana Mihályová, Ivo Demel, Barbora Dluhošová, Kateřina Benková, Juraj Ďuraš, Soňa Kolářová, Veronika Hanzelková, Simona Pulcerová, Roman Hájek   +13 more
wiley   +1 more source

Prognostic implications of right ventricular to pulmonary artery uncoupling in cardiac amyloidosis

Frontiers in Cardiovascular Medicine
BackgroundRight ventricular–pulmonary arterial (RV–PA) uncoupling in cardiac amyloidosis (CA) has been underexplored, with focus mainly on tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP).
Aiste Monika Jakstaite, Aiste Monika Jakstaite, Anja Hänselmann, Anja Hänselmann, Samira Soltani, Samira Soltani, Eleonora Angelini, Eleonora Angelini, Michael Heuser, Michael Heuser, Michael Heuser, Vega Gödecke, Vega Gödecke, Stefan Gingele, Stefan Gingele, Thomas Skripuletz, Thomas Skripuletz, Johann Bauersachs, Johann Bauersachs, Udo Bavendiek, Udo Bavendiek, Dominik Berliner, Dominik Berliner   +22 more
doaj   +1 more source

Primary localized conjunctival amyloidosis: A case report with a ten-year follow-up period

, 2008
Juan Carlos Mesa-Gutiérrez, Tomás Martí Huguet, Noemí Barnils Garcia, Jorge Arruga GinebredaDepartment of Ophthalmology, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Barcelona ...
Jorge Arruga Ginebreda, Noemí Barnils Garcia, Juan Carlos Mesa-Gutiérrez, Tomás Martí Huguet   +3 more
core  

Systemic reactive (AA) amyloidosis in the course of common variable immunodeficiency

, 2010
Patients with primary immunodeficiencies (PID) are currently at low risk for the development of systemic reactive AA amyloidosis. A patient with common variable immunodeficiency and nephrotic syndrome was referred to our Clinic from a Nephrology unit ...
Peralta M. M., Frau A., MANCONI, PAOLO EMILIO, Spiga S., Lorrai M. M., Grande M., Collu F., FIRINU, DAVIDE, Murgia G., Serusi L., Barca M. P.   +10 more
core   +1 more source

Role of FibroScan in evaluating hepatic involvement in systemic amyloidosis: a single‐centre prospective pilot study

Internal Medicine Journal, EarlyView.
Abstract Background Amyloidosis encompasses a group of diseases characterised by extracellular deposition of misfolded protein fibrils, potentially leading to organ dysfunction. Liver involvement occurs via direct amyloid infiltration, common in immunoglobulin light chain (AL) amyloidosis, or congestive hepatopathy, more typical in transthyretin (ATTR)
M Tang, N Vootukuru, J Tjahyadi, D Clayton Chubb, H Jina, SB Ting, S Bloom, R Sawhney, S Gibbs, O. Niewiadomski   +9 more
wiley   +1 more source

Atrial fibrillation in the setting of cardiac amyloidosis - A review of the literature.

Cardiac amyloidosis (CA) is related to the aggregation of insoluble fibrous deposits of misfolded proteins within the myocardium. Transthyretin amyloidosis (ATTR) and immunoglobulin light-chain amyloidosis are the main forms of CA.
Letsas, Konstantinos P, Tse, Gary, Sfairopoulos, Dimitrios, Stavrakis, Stavros, Saplaouras, Athanasios, Liu, Tong, Thomopoulos, Costas, Korantzopoulos, Panagiotis, Yiannikourides, Andronicos, Bazoukis, George, Efthymiou, Polyxeni, Varrias, Dimitrios   +11 more
core   +1 more source

Feasibility, Safety, and Efficacy of Pulsed Field Ablation for Ventricular Arrhythmias: Insights From a Large Health System Registry in the United States

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging non‐thermal ablation modality with proven safety in atrial arrhythmia ablation. However, data on its performance for ventricular arrhythmias (VA) remain limited. Objective To evaluate the feasibility, safety, and efficacy of PFA for complex VA in a multicenter real‐world US registry ...
Narut Prasitlumkum, Juan F. Rodriguez‐Riascos, Hema Vemulapalli, Aakash Somappa, Camilo A. Estrada‐Vargas, Olubadewa A. Fatunde, Carlos A. Rojas, Poojan Prajapati, Keerthika Vijayakumar, Suraj Kapa, Duy Nguyen, Samuel Asirvatham, Malini Madhavan, Christopher McLeod, Hicham Z. El Masry, Abhishek J. Deshmukh, Danesh K. Kella, Ammar M. Killu, Siva K. Mulpuru, Mayank Sardana, Luis R. Scott, Alan M. Sugrue, Komandoor Srivathsan   +22 more
wiley   +1 more source

A new staging system for hereditary transthyretin amyloidosis in the era of specific amyloidosis therapies

ESC Heart Failure
Objectives Currently, there are two prognosis staging systems validated for transthyretin amyloidosis (ATTR). We sought to develop a new staging system dedicated to hereditary transthyretin amyloidosis (ATTRv) patients on specific treatments. Methods and
Gabriela Neculae, Amira Zaroui, Robert Adam, Mounira Kharoubi, Benoit Funalot, Daniel Coriu, Ruxandra Jurcut, Thibaud Damy   +7 more
doaj   +1 more source

Clinical trials portfolio and regulatory outcomes of ixazomib in multiple myeloma: A systematic review and meta‐analysis

British Journal of Haematology, EarlyView.
Veer Shah, Darshi Shah, Payton Utzman, Karan Shah, Srivatsan Swaminathan, Maria Mainou, Rajshekhar Chakraborty, Aaron Goodman, Samer Al Hadidi, Amar H. Kelkar, Edward R. Scheffer Cliff, Ghulam Rehman Mohyuddin   +11 more
wiley   +1 more source