Results 21 to 30 of about 148,501 (250)

Different observation period of exercise training in amyotrophic lateral sclerosis patients: A meta-analysis

Frontiers in Neurology, 2022
ObjectiveThe purpose of this meta-analysis was to evaluate the effect of more intensive exercise training on the functional ability of patients with amyotrophic lateral sclerosis.MethodsRandomized controlled trials on exercise training in amyotrophic ...
Baohua Zhou, Jiajun Wei, Yanli Zhang, Yue Liu, Shuhui Shan, Shan Ye, Baohua Li, Dongsheng Fan, Yongmei Luo   +8 more
doaj   +1 more source

Control in the absence of choice: A qualitative study on decision-making about gastrostomy in people with amyotrophic lateral sclerosis, caregivers, and healthcare professionals.

PLoS ONE, 2023
BackgroundGastrostomy is recommended in amyotrophic lateral sclerosis for long-term nutritional support, however, people with amyotrophic lateral sclerosis and healthcare professionals perceive decision-making as complex.MethodTo explore their ...
Remko M van Eenennaam, Neele Rave, Willeke J Kruithof, Esther T Kruitwagen-van Reenen, Leonard H van den Berg, Johanna A Visser-Meily, Anita Beelen   +6 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis: An Analysis of the Electromyographic Fatigue of the Masticatory Muscles

Prague Medical Report, 2022
Amyotrophic lateral sclerosis is a chronic degenerative disease that affects motor neurons, thereby promoting functional changes in the human body.
Ligia Maria Napolitano Gonçalves, Selma Siéssere, Flávia Argentato Cecilio, Jaime Eduardo Cecilio Hallak, Paulo Batista de Vasconcelos, Wilson Marques Júnior, Isabela Hallak Regalo, Marcelo Palinkas, Simone Cecilio Hallak Regalo   +8 more
doaj   +1 more source

Amyotrophic lateral sclerosis modifies progenitor neural proliferation in adult classic neurogenic brain niches

BMC Neurology, 2017
Background Adult neurogenesis persists through life at least in classic neurogenic niches. Neurogenesis has been previously described as reduced in neurodegenerative diseases.
Lucía Galán, Ulises Gómez-Pinedo, Antonio Guerrero, Jose Manuel García-Verdugo, Jorge Matías-Guiu   +4 more
doaj   +1 more source

Microstructural Correlates of Emotional Attribution Impairment in Non-Demented Patients with Amyotrophic Lateral Sclerosis. [PDF]

PLoS ONE, 2016
Impairments in the ability to recognize and attribute emotional states to others have been described in amyotrophic lateral sclerosis patients and linked to the dysfunction of key nodes of the emotional empathy network. Microstructural correlates of such
Chiara Crespi, Chiara Cerami, Alessandra Dodich, Nicola Canessa, Sandro Iannaccone, Massimo Corbo, Christian Lunetta, Andrea Falini, Stefano F Cappa   +8 more
doaj   +1 more source

Destination Amyotrophic Lateral Sclerosis [PDF]

Frontiers in Neurology, 2021
Amyotrophic Lateral Sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons both in the brain and spinal cord. The constantly evolving nature of ALS represents a fundamental dimension of individual differences that underlie this disorder, yet it involves multiple levels of functional ...
Keon, M, Musrie, B, Dinger, M, Brennan, SE, Santos, J, Saksena, NK   +5 more
openaire   +5 more sources

Sleep disorders of insomnia type in patients with amyotrophic lateral sclerosis

Нервно-мышечные болезни, 2017
Objective: to evaluate the rate of sleep disorders of insomnia type among patients with amyotrophic lateral sclerosis (ALS) and to study the connection between these disorders and clinical characteristics of the disease. Materials and methods.
G. N. Levitskiy, M. G. Poluektov
doaj   +1 more source

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

New England Journal of Medicine, 2020
BACKGROUND Sodium phenylbutyrate and taurursodiol have been found to reduce neuronal death in experimental models. The efficacy and safety of a combination of the two compounds in persons with amyotrophic lateral sclerosis (ALS) are not known.
S. Paganoni, E. Macklin, S. Hendrix, J. Berry, Michael A. Elliott, S. Maiser, C. Karam, J. Caress, M. Owegi, Adam Quick, J. Wymer, Stephen A. Goutman, Daragh Heitzman, T. Heiman-Patterson, C. Jackson, C. Quinn, J. Rothstein, E. Kasarskis, J. Katz, Liberty Jenkins, S. Ladha, T. Miller, S. Scelsa, Tuan-Ha Vu, Christina N. Fournier, J. Glass, Kristina Johnson, A. Swenson, N. Goyal, G. Pattee, P. Andres, Suma Babu, Marianne K Chase, D. Dagostino, S. Dickson, N. Ellison, Meghan Hall, K. Hendrix, Gale Kittle, Michelle M. McGovern, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, J. Shefner, A. Sherman, E. Tustison, P. Vigneswaran, Jason Walker, Hong Yu, James Chan, J. Wittes, J. Cohen, J. Klee, K. Leslie, R. Tanzi, Walter Gilbert, P. Yeramian, D. Schoenfeld, M. Cudkowicz   +58 more
semanticscholar   +1 more source

Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases

Brain : a journal of neurology, 2021
Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances in other neurodegenerative diseases offer valuable insights.
M. Benatar, J. Wuu, Caroline A. McHutchison, R. Postuma, B. Boeve, R. Petersen, C. Ross, H. Rosen, Jalayne J. Arias, S. Fradette, M. Mcdermott, J. Shefner, Christine Stanislaw, S. Abrahams, Stephanie Cosentino, P. Andersen, R. Finkel, V. Granit, Anne-Laure Grignon, J. Rohrer, C. Mcmillan, M. Grossman, A. Al-Chalabi, M. R. Turner   +23 more
semanticscholar   +1 more source

At-home wearables and machine learning sensitively capture disease progression in amyotrophic lateral sclerosis

Nature Communications, 2023
Amyotrophic lateral sclerosis causes degeneration of motor neurons, resulting in progressive muscle weakness and impairment in motor function. Promising drug development efforts have accelerated in amyotrophic lateral sclerosis, but are constrained by a ...
Anoopum S. Gupta, Siddharth Patel, Alan Premasiri, Fernando Vieira   +3 more
doaj   +1 more source