Results 1 to 10 of about 2,700,197 (262)

Motor Neuron Disease: The Contribution of TAR-43 Gene in Amyotrophic Lateral Sclerosis [PDF]

Bengal Physician Journal, 2023
Motor neuron diseases are a spectrum of neurodegenerative disorders, characterized by their physicochemical propinquity for the voluntary motor systems. The most notorious of these neurodegenerative disorders is amyotrophic lateral sclerosis (ALS), which
Gorky Guha
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Investigating the Effectiveness of Acceptance and Commitment Therapy on Perceived Social Support and Life Expectancy of Caregivers of Patients with Amyotrophic Lateral Sclerosis (ALS): A Case Study [PDF]

مجله علوم پزشکی صدرا, 2023
Introduction: Caring for patients with amyotrophic lateral sclerosis (ALS) presents numerous challenges that can significantly impact caregivers. These challenges necessitate interventions to increase perceived social support and improve life expectancy.
Royasadat Shavaran, Akram Dehghani Champiri   +1 more
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High and Low Contrast Visual Acuity Are Not Affected in Amyotrophic Lateral Sclerosis. [PDF]

PLoS ONE, 2016
The afferent visual system may be affected by neuro-degeneration in amyotrophic lateral sclerosis (ALS) based on observations of visual function impairment and retinal inclusions on histopathology in ALS patients.
Heather E Moss, Monica Samelson, Girish Mohan, Qin Li Jiang   +3 more
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Early Referral to an ALS Center Reduces Several Months the Diagnostic Delay: A Multicenter-Based Study

Frontiers in Neurology, 2020
Objective: To analyze those factors contributing to the diagnostic delay in ALS.Methods: Consecutive ALS patients were categorized as those studied in departmental hospitals and those studied in a referral ALS center.
Marina Martínez-Molina, Marina Martínez-Molina, Herminia Argente-Escrig, Herminia Argente-Escrig, Margarita F. Polo, David Hervás, Marina Frasquet, Marina Frasquet, Victoria Cortés, Teresa Sevilla, Teresa Sevilla, Teresa Sevilla, Teresa Sevilla, Juan F. Vázquez-Costa, Juan F. Vázquez-Costa, Juan F. Vázquez-Costa, Juan F. Vázquez-Costa   +16 more
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Progressive brainstem pathology in motor neuron diseases: Imaging data from amyotrophic lateral sclerosis and primary lateral sclerosis

Data in Brief, 2020
A standardised, single-centre, longitudinal imaging protocol was used to evaluate longitudinal brainstem alterations in 100 patients with amyotrophic lateral sclerosis (ALS) with reference to 33 patients with primary lateral sclerosis (PLS), 30 patients ...
Peter Bede, Rangariroyashe H. Chipika, Eoin Finegan, Stacey Li Hi Shing, Kai Ming Chang, Mark A. Doherty, Jennifer C. Hengeveld, Alice Vajda, Siobhan Hutchinson, Colette Donaghy, Russell L. McLaughlin, Orla Hardiman   +11 more
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Case report: A variant of the FIG4 gene with rapidly progressive amyotrophic lateral sclerosis

Frontiers in Neurology, 2022
Heterozygous autosomal-dominant FIG4 mutations are associated with amyotrophic lateral sclerosis (ALS). Here, we describe a variant of the FIG4 gene (c.350dupC, p.Asp118GlyfsTer9) in a patient with rapidly progressive ALS that has not previously been ...
Mubalake Yilihamu, Mubalake Yilihamu, Mubalake Yilihamu, Xiaolu Liu, Xiaolu Liu, Xiaolu Liu, Xiaoxuan Liu, Xiaoxuan Liu, Xiaoxuan Liu, Yong Chen, Yong Chen, Yong Chen, Dongsheng Fan, Dongsheng Fan, Dongsheng Fan   +14 more
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Role of neuro-sonography of peripheral nerves as a diagnostic and a differentiation tool of amyotrophic lateral sclerosis

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Motor neuron disease is a heterogeneous group of progressive neurodegenerative disorders, most common of which is amyotrophic lateral sclerosis (ALS).
Rana Zakaria Ahmed Mohamed, Haitham Hamdy Salem, Hossam Moussa El-Sayed Sakr, Hossam-Eldin Mahmoud Afifi, Ahmed Mohammed Elsadek, Nagia Aly Fahmy   +5 more
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Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by GC/TOFMS. [PDF]

PLoS ONE, 2011
The changes in the cerebrospinal fluid (CSF) metabolome associated with the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS) are poorly understood and earlier smaller studies have shown conflicting results.
Anna Wuolikainen, Thomas Moritz, Stefan L Marklund, Henrik Antti, Peter Munch Andersen   +4 more
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MRI data confirm the selective involvement of thalamic and amygdalar nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis

Data in Brief, 2020
A standardised imaging protocol was implemented to evaluate disease burden in specific thalamic and amygdalar nuclei in 133 carefully phenotyped and genotyped motor neuron disease patients.
Rangariroyashe H. Chipika, We Fong Siah, Stacey Li Hi Shing, Eoin Finegan, Mary Clare McKenna, Foteini Christidi, Kai Ming Chang, Efstratios Karavasilis, Alice Vajda, Jennifer C. Hengeveld, Mark A. Doherty, Colette Donaghy, Siobhan Hutchinson, Russell L. McLaughlin, Orla Hardiman, Peter Bede   +15 more
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Difficulties in diagnosing amyotrophic lateral sclerosis in a HIV-Positive Patient

Журнал инфектологии, 2018
We described a case of amyotrophic lateral sclerosis (ALS) with comorbid HIV infection. The diagnosis was confirmed by genetic tests. The difficulty of the differential diagnosis between amyotrophic lateral sclerosis and HIV-associated ALS syndrome is ...
T. M. Alekseeva, N. V. Skripchenko, S. V. Lobzin, V. S. Demeshonok, E. A. Yurkina, V. D. Nazarov, S. V. Lapin   +6 more
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