Results 11 to 20 of about 49,177 (260)
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background Motor neuron disease is a heterogeneous group of progressive neurodegenerative disorders, most common of which is amyotrophic lateral sclerosis (ALS).
Rana Zakaria Ahmed Mohamed +5 more
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Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by GC/TOFMS. [PDF]
PLoS ONE, 2011 The changes in the cerebrospinal fluid (CSF) metabolome associated with the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS) are poorly understood and earlier smaller studies have shown conflicting results.
Anna Wuolikainen +4 more
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Data in Brief, 2020 A standardised imaging protocol was implemented to evaluate disease burden in specific thalamic and amygdalar nuclei in 133 carefully phenotyped and genotyped motor neuron disease patients.
Rangariroyashe H. Chipika +15 more
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Cognition and Amyotrophic Lateral Sclerosis (ALS)
American Journal of Alzheimer's Disease & Other Dementias®, 2007 Amyotrophic lateral sclerosis (ALS) is classically described as a pure motor disease; however, there is growing evidence of a range of cognitive impairment. Cognitive abnormalities include deficiencies in frontal executive skills, varying from mild deficits to meeting criteria for diagnosis of frontotemporal dementia (FTD).
D, Irwin, Carol F, Lippa, J M, Swearer
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Difficulties in diagnosing amyotrophic lateral sclerosis in a HIV-Positive Patient
Журнал инфектологии, 2018 We described a case of amyotrophic lateral sclerosis (ALS) with comorbid HIV infection. The diagnosis was confirmed by genetic tests. The difficulty of the differential diagnosis between amyotrophic lateral sclerosis and HIV-associated ALS syndrome is ...
T. M. Alekseeva +6 more
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Saccadic intrusions in amyotrophic lateral sclerosis (ALS)
Journal of Eye Movement Research, 2019 The attempt to steadily fixate at a small visual object is continuously interrupted by a variety of fixational eye movements comprising, among others, a continuum of saccadic intrusions (SI) which ranges in size from microsaccades with amplitudes ≤0.25° to larger refixation saccades of up to about 2°.
Wolfgang Becker +5 more
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Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS) [PDF]
Cold Spring Harbor Perspectives in Medicine, 2016 Amyotrophic lateral sclerosis (ALS) is primarily characterized by progressive loss of motor neurons, although there is marked phenotypic heterogeneity between cases. Typical, or "classical," ALS is associated with simultaneous upper motor neuron (UMN) and lower motor neuron (LMN) involvement at disease onset, whereas atypical forms, such as primary ...
Grad, Leslie +3 more
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Dysphagia as the Initial Presenting Symptom of Amyotrophic Lateral Sclerosis
Philippine Journal of Otolaryngology Head and Neck Surgery, 2008 Objective: To present a case of Amyotrophic Lateral Sclerosis (ALS) with an unusual initial presentation of dysphagia. Methods: Design: Case Report Setting: Private tertiary university hospital Patient: One Results: A 78-year-old ...
Adrian F. Fernando, Antonio H. Chua
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Induced pluripotent stem cell line derived from a sporadic amyotrophic lateral sclerosis patient
Stem Cell Research, 2020 Induced pluripotent stem cells (iPSCs) were generated from peripheral blood mononuclear cells (PBMCs) obtained from a 60-year-old female diagnosed with sporadic amyotrophic lateral sclerosis (sALS).
Baofeng Feng +12 more
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Diagnostics, 2023 Background: TAR DNA-binding protein 43 (TDP-43) aggregation in neuronal cells is recognized as a hallmark of amyotrophic lateral sclerosis (ALS). Although the literature strongly supports the pathogenetic role of TDP-43 in ALS pathogenesis, the role of ...
Caterina Maria Gambino +6 more
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