Results 191 to 200 of about 2,700,197 (262)

Greek Registry for Amyotrophic Lateral Sclerosis (ALS-GR): An Observational Cohort of Individuals With ALS Across 11 Specialized Centers in Greece. [PDF]

Eur J Neurol
Liampas I, Kimiskidis VK, Zouvelou V, Veltsista D, Moscholouri A, Triantafyllou E, Daponte A, Xirou S, Sterpi AE, Salakou S, Poulidou V, Arnaoutoglou M, Tsouris Z, Ralli S, Dardiotis E, Papagiannopoulos S, Zampetakis A, Zaganas Ι, Mitsias P, Giannakis A, Konitsiotis S, Kefalas F, Alexiou E, Stoiloudis P, Parissis D, Kiamelidis S, Terzoudi A, Tsivgoulis G, Rentzos M, Chroni E.   +29 more
europepmc   +1 more source

The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: An immunohistochemical study

Journal of Anatomy, EarlyView.
p‐STAT3‐positive cells in metabolically relevant peripheral organs and tissues from mice administered with recombinant CNTF (0.3 mg/kg). Abstract Administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight in both humans and experimental animals, where it also ameliorates hyperglycemia, hyperinsulinemia, and dyslipidemia ...
Chiara Galli, Georgia Colleluori, Jessica Perugini, Edoardo Scopini, Ilenia Severi, Gaia Grandin, Antonio Giordano   +6 more
wiley   +1 more source

To Treat or Not to Treat: A Scoping Review of Speech Treatment for Dysarthria in Amyotrophic Lateral Sclerosis (ALS). [PDF]

Healthcare (Basel)
Whelan BM, Aldridge D, Ruhle J, Whitelock P, Taubert S, Collins A, Kearney E, Charania S, Henderson RD, Wallace SJ, Mitchell C, Stipancic KL, Kuruvilla-Dugdale M, Vogel AP.   +13 more
europepmc   +1 more source

Neuroanatomy education through the years: Revisiting the teaching slides used by Sir Wilfrid Edward Le Gros Clark

Journal of Anatomy, EarlyView.
This paper examines the life and legacy of British anatomist Sir Wilfrid Le Gros Clark through his neuroanatomical teaching collection at the University of Oxford. The authors catalogued 103 specimens and analyzed selected slides—including cases of multiple sclerosis, amyotrophic lateral sclerosis, tabes dorsalis, syringomyelia, and the pineal gland's ...
Shiva A. Nischal, Kush M. Kale, Katherine Tourigny, Mohammed Abuelem, Gretchen Greene, Rachel Walsh, Zoltán Molnár   +6 more
wiley   +1 more source

Enlarged Perivascular Spaces (EPVS) and the Risk of Amyotrophic Lateral Sclerosis (ALS): Evidence for Overlapping Genetic Signals in White Matter Without Causal Links. [PDF]

Brain Sci
Huang X, Xia K, Ye S, Yang Q, Fan D.
europepmc   +1 more source

Caregiving and Respite for People With Motor Neurone Disease: A National Cross‐Sectional Survey of Experiences and Challenges

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To ascertain care support for people with motor neurone disease encompassing formal and informal care (funded and unfunded care), residential respite utilisation, care tasks performed by family members, and experiences and challenges encountered in accessing funded care. Design National cross‐sectional survey.
Natalie Gauld, Joanna Hikaka, Simone Newsham, Chris Frampton, Ruth Mylchreest, Tamzin Brott, Sarah M. Buchanan, Stephen Buetow   +7 more
wiley   +1 more source

Drug repurposing in amyotrophic lateral sclerosis (ALS). [PDF]

Expert Opin Drug Discov
Carroll E, Scaber J, Huber KVM, Brennan PE, Thompson AG, Turner MR, Talbot K.   +6 more
europepmc   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn, Fabian B. Haas, Benjamin G. Chavez, Bernd H. Dreyer, Erik V. Reiss, Anne Ziplys, Heiko Weichert, Saskia Hiltemann, José M. Ugalde, Andreas J. Meyer, John C. D'Auria, Stefan A. Rensing, Jos H. M. Schippers   +12 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source