Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
Importance of anabolic agents, binders, antioxidants and mould inhibitors in fish and prawn feeds [PDF]
D C Easterson, R Paulraj
openalex
Interdisciplinary care for users of anabolic agents in recreational sports in Switzerland – a first clinic has opened in Zurich [PDF]
M. J. Raphael, Bruggmann Philip
openalex +1 more source
Injectable and In Situ Hydration‐Reinforced Hybrid Bone Cements for Accelerated Bone Regeneration
To enable minimally invasive bone defect repair, an injectable and hydration‐reinforced bone cement (L‐PEGS/CPC) is designed through biomimetic reconstruction. The hydrophilic L‐PEGS organic phase provides abundant nucleation sites, synergizing with its porous architecture to accelerate CPC hydration, thereby endowing the composite with exceptional ...
Xing Chen +7 more
wiley +1 more source
Anabolic medications for rehabilitation after hip fracture in older people. [PDF]
Deacon C +5 more
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
PTH Analog Therapy in CKD G4-G5D: Current Evidence and Potential Role of Abaloparatide in Adynamic Bone Disease. [PDF]
Gifre L +11 more
europepmc +1 more source
Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand +2 more
wiley +1 more source
Preoperative treatment and postoperative outcomes in osteoporotic patients with vertebral fractures: a longitudinal database study. [PDF]
Koto R +4 more
europepmc +1 more source

