Results 171 to 180 of about 3,709,556 (294)

A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium‐Embedded Mesoporous Silica and Chitosan Nanoparticles

ChemistryOpen, Volume 15, Issue 3, March 2026.
Herein, solvent extraction was selected for cetyltrimethylammonium bromide removal and the development of optimized Se‐embedded mesoporous silica nanoparticles, which were loaded with enzalutamide. Additionally, to improve the anticancer activity of Se@MSNPs‐Enz and curcumin bioavailability, curcumin‐loaded chitosan nanoparticles were prepared. This pH‐
Zahra Tavakoli, Khosro Khajeh, Bijan Ranjbar   +2 more
wiley   +1 more source

Model‐Based Interpretation of Solute Exports and Carbon Partitioning During Shale Weathering in a Mountainous Hillslope

Water Resources Research, Volume 62, Issue 3, March 2026.
Abstract The weathering of sedimentary rocks in high‐elevation catchments influences freshwater quality and the global carbon cycle. While individual biogeochemical mechanisms involved in this process are relatively well understood, quantifying their contributions to solute export and carbon fluxes under natural, transient conditions remains ...
Lucien Stolze, Dipankar Dwivedi, Carl Steefel, Sergi Molins, Wenming Dong, Curtis Beutler, Alexander Newman, Kenneth Williams   +7 more
wiley   +1 more source

Nucleic acid-based therapeutics to restore joint homeostasis in age-related and post-traumatic arthritis. [PDF]

NPJ Biomed Innov
Rai MF, Pham CT, Hou K, Wickline SA, Pan H.   +4 more
europepmc   +1 more source

Endocrinological aspects of sarcopenic obesity. [PDF]

Ann Med
Minnetti M, Poggiogalle E, Frigerio F, Piciocchi C, Pierantozzi G, Di Vincenzo O, Pinto A, Gianfrilli D, Isidori AM, Migliaccio S, Donini LM.   +10 more
europepmc   +1 more source

The Influence of Extracellular Citrate in Physiological Concentration on the Proliferation of Malignant Melanoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT Cancer cells rely on citrate for multiple metabolic processes, suggesting that limiting the availability of extracellular citrate may represent a novel therapeutic strategy. The plasma membrane citrate transporter (pmCiC) has been implicated in the pathogenesis of several cancers before, and its activity can be inhibited by gluconate.
Konstantin Drexler, Barbara Schwertner, Veronika Zenderowski, Laura Schreieder, Dennis Christoph Harrer, Mark Berneburg, Edward Geissler, Maria Mycielska, Sebastian Haferkamp   +8 more
wiley   +1 more source

Astrocyte Bioenergetic Remodeling as a Central Trait of Disrupted Glucocorticoid Signaling: Mechanisms and Implications for Stress Vulnerability

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Low/brief glucocorticoid (GC) elevations can enhance mitochondrial output (↑ oxygen consumption rate, OCR; ↑ mitochondrial membrane potential, ΔΨm) and Ca2+ buffering, in part via glucocorticoid receptor (GR) trafficking to mitochondria in complexes with Bcl2 and Bag1.
Paweł Hanus, Dorota Frydecka, Michał Ślęzak   +2 more
wiley   +1 more source

Muscle loss and GLP-1R agonists use. [PDF]

Acta Diabetol
Rossi G, Bucciarelli L, Mananguite CL, Giovarelli M, Fiorina P.   +4 more
europepmc   +1 more source

Periodontal Health, Bite Force and Oral Health‐Related Quality of Life of Obese Older Adults Using Removable Partial Dentures

Journal of Oral Rehabilitation, Volume 53, Issue 3, Page 685-694, March 2026.
Impact of removable partial dentures on periodontal health, bite force, and oral health–related quality of life in obese versus normal‐weight older adults. Obese RPD wearers require closer periodontal management due to increased inflammation and lower OHRQoL.
Guilherme Fantini Ferreira, Talita Malini Carletti, Lorena Tavares Gama, Thais Marques Simek Vega Gonçalves, Renata Cunha Matheus Rodrigues Garcia   +4 more
wiley   +1 more source

A Molecular and Functional Investigation of the Anabolic Effect of an Essential Amino Acids' Blend Which Is Active In Vitro in Supporting Muscle Function. [PDF]

Nutrients
d'Adduzio L, Fanzaga M, Musco MS, Sindaco M, D'Incecco P, Boschin G, Bollati C, Lammi C.   +7 more
europepmc   +1 more source

Engineering Cyanobacteria for High‐Yield Photosynthetic Isoprene Production With Long‐Term Phenotypic Stability

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1014-1030, March 2026.
Center: Cyanobacterial isoprene production from CO2 and sunlight. Top: CRISPR‐editing for generation of markerless production strains. Top right: Long‐term production assay for strain stability assessment. Bottom right: Engineering of MEP pathway and surrounding metabolism for bottleneck idenfication. Bottom left: Relief of bottleneck by overproduction
Kim N. Janssen, Paul Bolay, Adrian Tüllinghoff, Jörg Toepel, Daniel Spindler, Bruno Bühler, Pia Lindberg   +6 more
wiley   +1 more source