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Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases

Bioorganic & Medicinal Chemistry, 2012
Lipoxygenases catalyze the oxidation of unsaturated fatty acids, such as linoleic acid, which play a crucial role in inflammatory responses. Selective inhibitors may provide a new therapeutic approach for inflammatory diseases. In this study, we describe the identification of a novel soybean lipoxygenase-1 (SLO-1) inhibitor and a potato 5-lipoxygenase (
Wisastra, Rosalina   +4 more
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Inhibition of lipoxygenase and prostaglandin endoperoxide synthase by anacardic acids

Biochemical and Biophysical Research Communications, 1991
C22:1 omega 5-anacardic acid was found to be a good inhibitor of both potato lipoxygenase and ovine prostaglandin endoperoxide synthase with approximate IC50's of 6 and 27 microM, respectively. Very similar inhibition was seen with the crude exudate, rich in omega 5-anacardic acids, from glandular trichomes of an arthropod-resistant strain of geranium,
R, Grazzini   +8 more
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Anacardic Acid: Molluscicide in Cashew Nut Shell Liquid

Planta Medica, 1982
The components of anacardic acid, (a mixture of 6-n-C (15) alkylsalicylic acids whose side chains vary in degrees of unsaturation) have been isolated by high pressure liquid chromatography from a crude extract of cashew nut shell, Anacardium occidentale, and tested for toxicity to fresh water snails, Biomphalaria glabrata.
J T, Sullivan   +3 more
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Structure-antibacterial activity relationships of anacardic acids

Journal of Agricultural and Food Chemistry, 1993
A series of anacardic acids possessing different side-chain lengths were synthesized, and their antimicrobial activity was tested. In the case against Staphylococcus aureus, the anacardic acid having the C 10 alkyl side chain was most active, while against Propionibacterium acnes, Streptococcus mutant, and Brevibacterium ammoniagenes, the anacardic ...
Isao. Kubo   +7 more
openaire   +1 more source

EFFICIENCY OF ANACARDIC ACID AS PRESERVATIVE IN TOMATO PRODUCTS

Journal of Food Processing and Preservation, 2008
Anacardic acid, 6[8′(Z), 11′(Z),14′-pentadecatrienyl] salicylic acid is the main active principle of Anacardium occidentale (Anacardiceae), the cashew. Cashew nut shell liquid (CNSL) contains approximately 70% anacardic acids, 18% cardol, 5% cardanol, and some other phenols and less polar substances. Because of the presence of anacardic acids, the CNSL
B. NARASIMHAN   +3 more
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The composition of the unsaturated phenolic components of anacardic acid

Journal of Chromatography A, 1971
Abstract The monoene, diene, and tiene components of anacardic acid have been quatitatively separated by argentation—thin-layer chromatography, and determined by ultraviolet spectrophotometry and gravimetry. Some progress has been made in the direct determination of the composition without separation of the component acids by use of nuclear magnetic ...
J.H.P. Tyman, N. Jacobs
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Antimicrobial effects of anacardic acids

Canadian Journal of Microbiology, 1969
Anacardic acids (6-alkylsalicylic acids) inhibited metabolism of Streptococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Gyrodinium cohnii, Euglena gracilis and a white mutant of it, Neurospora crassa, Penicillium griseofulvum, Saccharomyces cerevisiae, and Candida utilis. The Gram-positive B. subtilis and S.
J L, Gellerman   +3 more
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Enzymatic Polymerization of Natural Anacardic Acid and Antibiofouling Effects of Polyanacardic Acid Coatings

Applied Biochemistry and Biotechnology, 2008
Anacardic acid, separated from cashew nut shell liquid, is well known for its strong antibiotic and antioxidant activities. Recent findings indicate that phenolic compounds from plant sources have an effect on Gram-negative bacteria biofilm formation.
Chelikani, Rahul   +3 more
openaire   +3 more sources

ANACARDIC ACID

1967
TADEUSZ KORZYBSKI   +2 more
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Selective Ionophoric Properties of Anacardic Acid

Journal of Natural Products, 1995
K. S. Nagabhushana   +2 more
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