Results 61 to 70 of about 3,472 (209)
Cellular analysis of the action of epigenetics drugs and probes [PDF]
, 2017 Small molecule drugs and probes are important tools in drug discovery, pharmacology, and cell biology. This is of course also true for epigenetic inhibitors.
A. Ganesan +12 more
core +1 more source
Characterization of xanthine oxidase inhibition by anacardic acids
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2004 Anacardic acid, 6[8(Z), 11(Z), 14-pentadecatrienyl]salicylic acid, inhibits generation of superoxide radicals by xanthine oxidase. This inhibition does not follow a hyperbolic inhibition, depends on anacardic acid concentrations, but follows a sigmoidal inhibition. The inhibition was analyzed by using a Hill equation, and slope factor and EC(50) were 4.
Masuoka, Noriyoshi, Kubo, Isao
openaire +2 more sources
British Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley +1 more source
Clinical and Experimental Dental Research, Volume 11, Issue 6, December 2025.ABSTRACT Objectives Tooth erosion is the nonbacterial and irreversible pathological dissolution of enamel and dentin, and is primarily influenced by lifestyle. This systematic review and meta‐analysis aimed to evaluate the preventive and therapeutic effects of plant‐derived compounds on tooth erosion using evidence from in vitro and in situ studies ...
Mahtab Memarpour +5 more
wiley +1 more source
Evaluation of Lipoxygenase Inhibitory Activity of Anacardic Acids
Zeitschrift für Naturforschung C, 2008 6-Alkylsalicylic acids inhibit the linoleic acid peroxidation catalyzed by soybean lipoxygenase- 1 (EC 1.13.11.12, type 1) competitively and without pro-oxidant effects. This activity is largely dependent on the nature of their alkyl side chains. Inhibitory activities of anacardic acids, viz.
Isao, Kubo +4 more
openaire +2 more sources
Polymer Composites, Volume 46, Issue 16, Page 15089-15101, 10 November 2025.AgNPs were synthesized using Urtica dioica. AgNPs‐PU was prepared using a solution mixing method followed by spin coating. Microscopy Optical image of AgNPs‐PU composite with different concentrations of AgNPs. Electrical behaviour versus pressure. ABSTRACT This study explores the electrical properties of a nanocomposite composed of green‐synthesized ...
Saeid Mehvari +6 more
wiley +1 more source
MoleculesEllagic acid, known for its various biological activities, is widely used. Ellagic acid from pomegranate peels is safe for consumption, while that from gallnuts is only suitable for external use. However, there is currently no effective method to confirm
Jinchao Wei +5 more
doaj +1 more source
Conserved epigenetic mechanisms could play a key role in regulation of photosynthesis and development-related genes during needle development of Pinus radiata [PDF]
, 2015 Needle maturation is a complex process that involves cell growth, differentiation and tissue remodelling towards the acquisition of full physiological competence.
Cañal Villanueva, María Jesús Fátima +4 more
core +4 more sources
Uric Acid‐Lowering and Anti‐Hyperuricemia Effects of Plant‐Based Nutraceuticals and Foods: A Review
Food Chemistry International, Volume 1, Issue 3, Page 216-250, September 2025.Increased UA production and/or decreased UA secretion cause hyperuricemia. Effects and mechanism of flavonoids in reducing UA are summarized. Terpenoids, saponins, alkaloids, vitamin C, polysaccharides, peptides are effective. Plant‐based foods with UA‐lowering ability are reviewed.
Linwei He, Wenjian Yang, Jianhui Liu
wiley +1 more source
Molecular Oncology, Volume 19, Issue 8, Page 2166-2170, August 2025.Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source