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Evaluation of Lipoxygenase Inhibitory Activity of Anacardic Acids
Evaluation of Lipoxygenase Inhibitory Activity of Anacardic Acids6-Alkylsalicylic acids inhibit the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) competitively and without pro-oxidant effects. This activity is largely dependent on the nature of their alkyl side chains. Inhibitory activities of anacardic acids, viz.
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Extraction of Anacardic Acid and its Applications. A review
Journal of Science with Technological ApplicationsYair A Vega +5 more
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Lead chalcogenides stabilized by anacardic acid
Materials Science in Semiconductor Processing, 2013Abstract PbE (E=S, Se and Te) nanoparticles stabilized by anacardic acid in the shape of spheres and cubes have been synthesized employing a simple solution based thermolysis route at moderate reaction temperatures. The route adheres to some of the principles of ‘green’ chemistry since a naturally occurring capping ligand, anacardic acid, is employed
Neerish Revaprasadu +2 more
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Design and evaluation of anacardic acid derivatives as anticavity agents
European Journal of Medicinal Chemistry, 2008On the basis of antibacterial anacardic acids, 6-pentadecenylsalicylic acids, isolated from the cashew apple, Anacardium occidentale L. (Anacardiaceae), a series of 6-alk(en)ylsalicylic acids were synthesized and tested for their antibacterial activity against Streptococcus mutans ATCC 25175.
Ken-Ichi Nihei, Ivan Green
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Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity
European Journal of Medicinal Chemistry, 2009Several benzamide derivatives were synthesized from anacardic acid (1a) which was the product of hydrogenation of the naturally occurring anacardic acid mixture (1a-d), a major constituent of cashew nut shell liquid. Anacardic acid (1a) was first alkylated followed by hydrolysis of the ester to obtain synthones namely, 2-ethoxy-6-pentadecylbenzoic acid
Anil Kush
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Antibacterial Anacardic Acid Derivatives
ACS Infectious Diseases, 2020We report on the antibacterial activity of five phenolic lipids derived from anacardic acid characterized by increasing alkyl chain lengths with 6, 8, 10, 12, or 14 carbon atoms. The compounds were profiled for their physicochemical properties, transport across epithelial monolayers, cytotoxicity, and antibacterial activity as compared to common ...
Marco Saedtler +7 more
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Liebigs Annalen, 1995
AbstractThe anacardic acids 1–11, isolated from various plants, were synthesized by a new general method. Reaction of the methyl alkynoates 12–18 with 1‐methoxy‐1,4‐cyclohexadiene at 200°C afforded directly the methyl 2‐methoxybenzoates 19–25 with long chain substituents in 6‐position in 74–85% yield. The dienophiles 12–16 were prepared by pyrolysis of
Reinhard Zehnter, Hans Gerlach
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AbstractThe anacardic acids 1–11, isolated from various plants, were synthesized by a new general method. Reaction of the methyl alkynoates 12–18 with 1‐methoxy‐1,4‐cyclohexadiene at 200°C afforded directly the methyl 2‐methoxybenzoates 19–25 with long chain substituents in 6‐position in 74–85% yield. The dienophiles 12–16 were prepared by pyrolysis of
Reinhard Zehnter, Hans Gerlach
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Lipoxygenase Inhibitory Activity of Anacardic Acids
Journal of Agricultural and Food Chemistry, 20056[8'(Z)-pentadecenyl]salicylic acid, otherwise known as anacardic acid (C15:1), inhibited the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) with an IC50 of 6.8 microM. The inhibition of the enzyme by anacardic acid (C15:1) is a slow and reversible reaction without residual activity.
Tae Joung, Ha, Isao, Kubo
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Syntheses of anacardic acids and ginkgoic acid
Tetrahedron, 1987Abstract Syntheses of two anacardic acids [6-pentadecyl- and 6-(10-pentadecenyl) salicylic acid], inhibitors of prostaglandin synthetase and of the growth of certain insects, and ginkgoic acid via directive metallation is reported.
Yoshiro Yamagiwa +5 more
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Antioxidant activity of anacardic acids
Food Chemistry, 2006Abstract Anacardic acids, 6-pentadec(en)ylsalicylic acids isolated from the cashew Anacardium occidentale L. (Anacardiaceae) nut and apple, were found to possess preventive antioxidant activity while salicylic acid did not show this activity. These anacardic acids prevent generation of superoxide radicals by inhibiting xanthine oxidase (EC 1.1.3.22,
Isao Kubo +3 more
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