Results 61 to 70 of about 3,510 (204)

Emerging Therapeutic Strategies in Oral Cancer: Epigenetic, Mitochondrial and Immunotherapy Approaches

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer and poses treatment challenges owing to genetic, epigenetic and environmental factors. Conventional treatments, including surgery, chemotherapy and radiation therapy, often have limitations in terms of efficacy and tolerability.
Geetha Shanmugam, Carmelin Durai Singh, Rekha Thiruvengadam, Muthu Thiruvengadam, Vitaly Morozov, Roman Kolesnikov, Ali Alkaladi, Rashad Saleh, Mohammad Ali Shariati   +8 more
wiley   +1 more source

Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent Key Elements in ESC Pluripotency [PDF]

, 2017
Wnt/β-catenin signaling is required for embryonic stem cell (ESC) pluripotency by inducing mesodermal differentiation and inhibiting neuronal differentiation; however, how β-catenin counter-regulates these differentiation pathways is unknown.
Hoffmeyer, Katrin, Junghans, Dirk, Kanzler, Benoit, Kemler, Rolf   +3 more
core   +2 more sources

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

BMC Molecular and Cell Biology, 2023
Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear.
Jiawei Shang, Feng Zhao, Yongmei Cao, Feng Ping, Wei Wang, Yingchuan Li   +5 more
doaj   +1 more source

Liposomal drug delivery systems and anticancer drugs [PDF]

, 2018
Cancer is a life-threatening disease contributing to ~3.4 million deaths worldwide. There are various causes of cancer, such as smoking, being overweight or obese, intake of processed meat, radiation, family history, stress, environmental factors, and ...
Elkordy, Amal Ali, Haj Ahmad, Rita Rushdi, Ibegbu, Daniel M., Olusanya, Temidayo O. B., Smith, James   +4 more
core   +3 more sources

Evaluation of Lipoxygenase Inhibitory Activity of Anacardic Acids

Zeitschrift für Naturforschung C, 2008
6-Alkylsalicylic acids inhibit the linoleic acid peroxidation catalyzed by soybean lipoxygenase- 1 (EC 1.13.11.12, type 1) competitively and without pro-oxidant effects. This activity is largely dependent on the nature of their alkyl side chains. Inhibitory activities of anacardic acids, viz.
Isao, Kubo, Tae Joung, Ha, Kazuo, Tsujimoto, Felismino E, Tocoli, Ivan R, Green   +4 more
openaire   +2 more sources

A multiscale approach to evaluate the effect of different extraction and pre‐treatment methodologies on physicochemical properties of cashew (Anacardium occidentale L.) nut shell liquid

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 2, Page 266-275, February 2026.
Abstract BACKGROUND Cashew nutshell liquid (CNSL) is an agro‐industrial residue from cashew production that has gained relevance due to its possibilities to generate valuable by‐products. Although lab‐scale CNSL extraction has been studied in terms of yield and energy efficiency, the effect of industrial‐scale extraction and nut pre‐treatment methods ...
Johan León, Gabriela Ortiz, Oscar Álvarez, Andres Fernando Gonzalez Barrios, Alejandro Maranon, Camilo Hernandez, Camilo Ayala, Alicia Porras   +7 more
wiley   +1 more source

Conserved epigenetic mechanisms could play a key role in regulation of photosynthesis and development-related genes during needle development of Pinus radiata [PDF]

, 2015
Needle maturation is a complex process that involves cell growth, differentiation and tissue remodelling towards the acquisition of full physiological competence.
Cañal Villanueva, María Jesús Fátima, Escandón Martínez, Mónica, Meijón Vidal, Mónica, Pascual Vázquez, Jesús, Valledor González, Luis   +4 more
core   +4 more sources

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines – in vitro studies

International Journal of Nanomedicine, 2014
Mateusz Legut, Dominik Lipka, Nina Filipczak, Adriana Piwoni, Arkadiusz Kozubek, Jerzy GubernatorDepartment of Lipids and Liposomes, Faculty of Biotechnology, University of Wrocław, Wrocław, PolandAbstract: This paper describes a novel formulation of ...
Legut M, Lipka D, Filipczak N, Piwoni A, Kozubek A, Gubernator J   +5 more
doaj  

Optimising the Decarboxylation of Anacardic Acid by Exploring the Temperature Effects

Journal of Chemistry
Cashew nut shell liquid (CNSL) is one of the raw materials extracted from cashew nut shells (CNS). This liquid can be processed to produce cardanol through the decarboxylation of anacardic acid, a significant isolate from CNSL.
Eva G. Nyoni, Petro E. Mabeyo, Aldo J. Kitalika   +2 more
doaj   +1 more source