Results 101 to 110 of about 350,338 (294)
Advanced Science, EarlyView.In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang +12 more
wiley +1 more source
Glycolytic activity of the tissue stem cells in the macula flava of the human vocal fold
Laryngoscope Investigative Otolaryngology, 2021 Objectives In our previous studies, the features of the mitochondria of tissue stem cells in the maculae flavae of the human vocal fold suggested that their metabolic activity and oxidative phosphorylation was low.
Kiminori Sato +5 more
doaj +1 more source
Functional optimization of the arterial network [PDF]
, 2014 We build an evolutionary scenario that explains how some crucial physiological constraints in the arterial network of mammals - i.e. hematocrit, vessels diameters and arterial pressure drops - could have been selected by evolution.
Mauroy, Benjamin, Moreau, Baptiste
core
A fast ethanol assay to detect seed deterioration [PDF]
, 2012 The most common way to test seed quality is to use a simple and reliable but time- and space-consuming germination test. In this paper we present a fast and simple method to analyse cabbage seed deterioration by measuring ethanol production from ...
Buckley, W.T. +5 more
core +2 more sources
Advanced Science, EarlyView.This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu +10 more
wiley +1 more source
Microorganisms, 2020 Mycobacterium abscessus subsp. abscessus (MAB) is a clinically important nontuberculous mycobacterium (NTM) causing pulmonary infection in patients such as cystic fibrosis and bronchiectasis.
Rajoana Rojony +5 more
doaj +1 more source
Advanced Science, EarlyView.Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang +13 more
wiley +1 more source
The Prolyl Hydroxylase Domain 2 (PHD2) Deficiency Enhances Maximal Exercise Capacity [PDF]
운동과학PURPOSE Hypoxic training is beneficial for improving endurance performance. Hypoxia-inducible factor (HIF) is a key transcription factor that regulates the hypoxic-responsive pathway. Stabilization of HIF by inactivating prolyl hydroxylase domain protein
Junchul Shin
doaj +1 more source
HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]
, 2013 Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan +9 more
core +3 more sources
A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani +5 more
wiley +1 more source