Results 131 to 140 of about 350,338 (294)

Pasteur effect in leukocyte energy metabolism of patients with mild, moderate, and severe COVID-19

open access: yesTürk Biyokimya Dergisi
The Pasteur effect in cellular energy metabolism is defined as the switch to anaerobic glycolysis due to alterations in ambient oxygen concentration or inhibition of the electron transport chain (ETC) and oxidative phosphorylation.
Ortatatli Mesut   +5 more
doaj   +1 more source

Surgical site infections and sepsis in gynecological surgery

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento   +13 more
wiley   +1 more source

The Role of Tissue Oxygen Tension in Dengue Virus Replication

open access: yesCells, 2018
Low oxygen tension exerts a profound effect on the replication of several DNA and RNA viruses. In vitro propagation of Dengue virus (DENV) has been conventionally studied under atmospheric oxygen levels despite that in vivo, the tissue microenvironment ...
Efseveia Frakolaki   +10 more
doaj   +1 more source

Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes

open access: yesiMetaOmics, EarlyView.
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alternation in lipid composition and metabolic phenotypes of Prmt5AKO mice. Abstract The adipose tissue (AT) is a main regulator of systemic energy homeostasis,
Xiyue Chen   +7 more
wiley   +1 more source

Closer to the Heart: Cardiac Muscle Aerobic Capacity Correlates With Intraspecific Variation in Sprint Performance Rather Than Androgen Levels in the Neotropical Lizard Tropidurus catalanensis

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
In male lizards Tropidurus catalanensis, sprint locomotor performance correlates with cardiac aerobic capacity. ABSTRACT Assessments of the interplay between physiology and whole‐organism performance are fundamental to understand how individuals function in different ecological contexts.
Willian Souza Lima   +3 more
wiley   +1 more source

Microplastics in Agricultural Soil: Fate, Impacts, and Bioremediation by Earthworms

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
Microplastics enter the soil through various means, including the degradation of plastic film mulch, waste from cosmetics industries and municipalities, and the use of bioplastic seed coatings. These microplastics disrupt soil structure, microbial activity, enzyme function, and plant growth.
Sami ur Rehman   +5 more
wiley   +1 more source

Vitexin Attenuates the Growth and Glycolysis of Acute Myeloid Leukemia Cells by Suppressing the HIF‐1α‐Modulated YAP Pathway Under Hypoxic Conditions

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vitexin, an apigenin flavone glycoside, exhibits antitumor activity against various cancers including leukemia. Hypoxia enhances glycolysis, thereby promoting tumor growth. In this study, we aimed to explore the effects of vitexin on hypoxia‐induced growth and glycolysis in acute myeloid leukemia (AML) cells and determine the underlying ...
Ping Wang   +4 more
wiley   +1 more source

Immunometabolic effects of lactate on humoral immunity in healthy individuals of different ages

open access: yesNature Communications
Aging is characterized by chronic systemic inflammation and metabolic changes. We compare the metabolic status of B cells from young and elderly donors and found that aging is associated with higher oxygen consumption rates, and especially higher ...
Maria Romero   +6 more
doaj   +1 more source

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