Results 71 to 80 of about 350,338 (294)

Mechanisms of adaptation to intensive loads of 400 meters’ hurdles runners at stage of initial basic training

Physical Education of Students, 2015
Purpose: is study of adaptation mechanisms of 400 meter’ hurdles-runners to intensive physical loads. Material: in the research 13 - 400 meters’ hurdles-runners and 13 - 400 meters’ runners participated.
A.S. Rovniy, V.M. Lastochkin
doaj   +1 more source

Hepatocellular carcinoma: Review of disease and tumor biomarkers. [PDF]

, 2016
© The Author(s) 2016.Hepatocellular carcinoma (HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative
Cox, IJ, Crossey, MM, Fye, HK, Gomez-Romero, M, Holmes, E, Kim, JU, Njie, R, Shariff, MI, Taylor-Robinson, SD   +8 more
core   +1 more source

Interactions Between Active Matters and Endogenous Fields

Advanced Materials, EarlyView.
This review synthesizes endogenous field information and computational methods in contexts such as cancer, wounds, and biofilms. It organizes NAMs and AAMs by sensing, transmitting, and executing functions, compares their limitations, and from these contrasts proposes design strategies for next‐generation AAMs, offering perspectives to foster ...
Jinwei Lin, Qiaoxin Guan, Jiangqi Feng, Shuqin Chen, Leilei Xu, Jianguo Guan, Samuel Sánchez   +6 more
wiley   +1 more source

Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis

Frontiers in Oncology, 2020
Pyruvate kinase plays a pivotal role in regulating cell metabolism. The final and rate-limiting step of glycolysis is the conversion of Phosphoenolpyruvate (PEP) to Pyruvate, which is catalyzed by Pyruvate Kinase. There are four isomeric, tissue-specific
Kulsoom Zahra, Tulika Dey, Ashish, Surendra Pratap Mishra, Uma Pandey   +4 more
doaj   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
A Vazquez, A Vazquez, A Vazquez, Alexei Vazquez, AV Hill, B Lee, D Voet, DA Hume, DG Hardie, DJ Marcinek, DR Wise, E Blomstrand, G Parra-Bonilla, H Hoppeler, J Achten, J Schellenberger, JM Savinell, JW Locasale, K Schwerzmann, K Sheikh, KE Conley, KR Short, MC Hogan, MG Vander Heiden, MJ Joyner, O Trabold, O Warburg, P Gao, PA Farrell, PR Rich, QK Beg, R Wibom, R Williams, RJ DeBerardinis, RK Scopes, T Shlomi, T Wang, U Glas, W Hu, WF Kemper, WH Munyon, XY Hou, Y Liu, Y Liu, Y Sidorenko, Yamir Moreno, Zoltán N. Oltvai   +46 more
core   +6 more sources

Adenosine Triphosphate and Carbon Efficient Route to Second Generation Biofuel Isopentanol. [PDF]

, 2020
Climate change necessitates the development of CO2 neutral or negative routes to chemicals currently produced from fossil carbon. In this paper we demonstrate a pathway from the renewable resource glucose to next generation biofuel isopentanol by pairing
Chiniquy, Jennifer, Eiben, Christopher B, Goyal, Garima, Hillson, Nathan J, Kaplan, Nurgul, Keasling, Jay D, Lee, Taek Soon, Mendez-Perez, Daniel, Thompson, Mitchell G, Tian, Tian   +9 more
core   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Transcriptomic signature of Leishmania infected mice macrophages: a metabolic point of view.

PLoS Neglected Tropical Diseases, 2012
We analyzed the transcriptional signatures of mouse bone marrow-derived macrophages at different times after infection with promastigotes of the protozoan parasite Leishmania major.
Imen Rabhi, Sameh Rabhi, Rym Ben-Othman, Axel Rasche, Adriani Daskalaki, Bernadette Trentin, David Piquemal, Béatrice Regnault, Albert Descoteaux, Lamia Guizani-Tabbane, Sysco Consortium   +10 more
doaj   +1 more source

Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis

JID Innovations, 2021
Alterations of the lipid profile of the stratum corneum have an important role in the pathogenesis of atopic dermatitis (AD) because they contribute to epidermal barrier impairment. However, they have not previously been envisioned as a cellular response
Petra Pavel, Géraldine Leman, Martin Hermann, Christian Ploner, Thomas O. Eichmann, Deborah Minzaghi, Franz P.W. Radner, Barbara Del Frari, Robert Gruber, Sandrine Dubrac   +9 more
doaj   +1 more source

Reviewer #1 (Public Review): Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis [PDF]

, 2023

openalex   +1 more source