The anaerobic threshold: 50+ years of controversy
The anaerobic threshold (AT) remains a widely recognized, and contentious, concept in exercise physiology and medicine. As conceived by Karlman Wasserman, the AT coalesced the increase of blood lactate concentration ([La−]), during a progressive exercise
D. Poole+3 more
semanticscholar +1 more source
INDUCTION OF ANAEROBIC PROCESSES IN BAIKAL ENDEMICS EULIMNOGAMMARUS VITTATUS (DYB.) AND E. VERRUCOSUS (DYB.) (AMPHIPODA, CRUSTACEA) [PDF]
The data confirming the ability of Baikalian endemic species Eulimnogammarus vittatus (Dyb.) and E. verrucosus (Dyb.) to activate anaerobic glycolysis under hypoxia are presented. The differences in the degree and the rate of lactic acid accumulation and
Timofeyev M.A.+5 more
doaj
A qualitative study of an anaerobic food-web reveals the importance of hydrogen for microbial stability [PDF]
The mathematical analysis of a three-tiered food-web describing anaerobic chlorophenol mineralisation has suggested the emergence of interesting dynamical behaviour through its specific ecological interactions, which include competition, syntrophy and product inhibition.
arxiv +1 more source
Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH. [PDF]
The microbial adaptations to the respiratory burst remain poorly understood, and establishing how the NADPH oxidase (NOX2) kills microbes has proven elusive. Here we demonstrate that NOX2 collapses the ΔpH of intracellular Salmonella Typhimurium.
Chakraborty, Sangeeta+7 more
core
The role and mechanism of histone lactylation in health and diseases
Whether under anaerobic or aerobic conditions, glycolysis results in production of lactate. Increasing evidence suggests that lactate serves as a multifunctional signaling molecule that develops non-metabolic activities in addition to serving as a key ...
Yumei Xie+6 more
doaj +1 more source
Characterization of pig skeletal muscle transcriptomes in response to low temperature
Low temperature changes the gene expression pattern and biological pathway in pig skeletal muscle. Under low temperature, biological pathways of lipid, amino acid, and carbohydrate metabolism; signal transduction; endocrine, immune, and nervous system; cardiovascular disease; infectious diseases caused by bacteria or viruses; and neurodegenerative ...
DongJie Zhang+4 more
wiley +1 more source
A modeling and simulation study of anaerobic digestion in plug-flow reactors [PDF]
A mathematical model for anaerobic digestion in plug-flow reactors is proposed on the basis of mass balance considerations. The model consists of a system of parabolic partial differential equations for the variables representing the concentrations of the bio-components constituting the waste matrix and takes into account convective and diffusive ...
arxiv +1 more source
Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
DYCK P. J.+11 more
core +1 more source
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
Safe anaerobic metabolism Naked mole-rats live in large colonies deep underground in hypoxic conditions. Park et al. found that these animals fuel anaerobic glycolysis with fructose by a rewired pathway that avoids tissue damage (see the Perspective by ...
T. Park+25 more
semanticscholar +1 more source
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song+8 more
wiley +1 more source