Results 41 to 50 of about 414,941 (338)

Systematic review and evidence synthesis of non-cervical human papillomavirus-related disease health systems costs and quality of life estimates [PDF]

, 2018
BACKGROUND: Many economic evaluations of human papillomavirus vaccination should ideally consider multiple disease outcomes, including anogenital warts, respiratory papillomatosis and non-cervical cancers (eg, anal, oropharyngeal, penile, vulvar and ...
Burns, L, Checci, M, Jit, M, Ong, KJ, Pavitt, C, Postma, M   +5 more
core   +3 more sources

Association analysis of gut microbiota with LDL-C metabolism and microbial pathogenicity in colorectal cancer patients

Lipids in Health and Disease
Background Colorectal cancer (CRC) is the most common gastrointestinal malignancy worldwide, with obesity-induced lipid metabolism disorders playing a crucial role in its progression. A complex connection exists between gut microbiota and the development
Mingjian Qin, Zigui Huang, Yongqi Huang, Xiaoliang Huang, Chuanbin Chen, Yongzhi Wu, Zhen Wang, Fuhai He, Binzhe Tang, Chenyan Long, Xianwei Mo, Jungang Liu, Weizhong Tang   +12 more
doaj   +1 more source

Initiation of an anal cancer screening in HIV+MSM: results of cytology, biopsy and determination of risk factors [PDF]

, 2012
Incidence of anal cancer is increasing and risk of anal cancer is higher in MSM, especially if they are HIV+. European guidelines for treatment of HIV-infected adults recommend anal cancer screening by digital rectal exam±Pap test with anuscopy if
A Libois, F Feoli, M Delforge, M Nkuize, N Clumeck, S De Wit   +5 more
core   +2 more sources

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Analysis of differences in intestinal flora associated with different BMI status in colorectal cancer patients

Journal of Translational Medicine
Background Overweight is known to be an important risk factor for colorectal cancer (CRC), and the differences in intestinal flora among CRC patients with different BMI status have not been clearly defined.
Yongqi Huang, Xiaoliang Huang, Zhen Wang, Fuhai He, Zigui Huang, Chuanbin Chen, Binzhe Tang, Mingjian Qin, Yongzhi Wu, Chenyan Long, Weizhong Tang, Xianwei Mo, Jungang Liu   +12 more
doaj   +1 more source

27 Association of anal dysplasia with cervical dysplasia and high-risk HPV subtypes in women

Gynecologic Oncology Reports, 2023
Objectives: High-risk human papillomavirus (hrHPV) infection is a necessary risk factor for cervical and anal dysplasia. Over the last five years, there is increasing evidence that the natural history of hrHPV-induced anal cancer is close to that of ...
Sonal Chaudhari, Sanaz Memarzadeh, Ardis Moe   +2 more
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Applications of Graphene Quantum Dots in Biomedical Sensors [PDF]

, 2020
Due to the proliferative cancer rates, cardiovascular diseases, neurodegenerative disorders, autoimmune diseases and a plethora of infections across the globe, it is essential to introduce strategies that can rapidly and specifically detect the ultralow ...
Altintas, Zeynep, Mansuriya, Bhargav D.
core   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Epidemiology of Any and Vaccine-Type Anogenital Human Papillomavirus Among 13-26-Year-Old Young Men After HPV Vaccine Introduction [PDF]

, 2018
PURPOSE: The aims of this study were to determine prevalence of and factors associated with any human papillomavirus (HPV) and vaccine-type HPV among young men after vaccine introduction, stratified by vaccination status.
Bernstein, David I., Brown, Darron A., Chandler, Emmanuel, Ding, Lili, Franco, Eduardo L., Gorbach, Pamina, Kahn, Jessica A., Widdice, Lea E.   +7 more
core   +1 more source