Results 81 to 90 of about 414,941 (338)

NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss [PDF]

, 2018
Background: The NCI-MATCH trial is the largest national study (1173 sites) for ptswith relapsed/ refractory solid tumors, lymphomas and myeloma, which assigns tar-geted therapies based on individual tumor molecular alterations detected using theadapted ...
Arteaga, C., Chen, A. P., Conley, B. A., Doyle, L. A., Flaherty, K. T., Hamilton, S. R., Harris, L. N., Janku, F., Jegede, O., Konstantinopoulos, P., Li, S., McShane, L. M., Meric-Bernstam, F., Mitchell, E. P, O\u27Dwyer, P. J., Patton, D., Puhalla, S. L., Rubinstein, L. V., Williams, P. M., Zwiebel, J. A.   +19 more
core   +1 more source

Transanal minimally invasive surgery for rectal lesions [PDF]

, 2016
Background and Objectives: Transanal minimally invasive surgery (TAMIS) has emerged as an alternative to transanal endoscopic microsurgery (TEM). The authors report their experience with TAMIS for the treatment of mid and high rectal tumors.
Balla, Andrea, Di Lorenzo, Nicola, Franceschilli, Luana, Iafrate, Corrado, La Torre, Marco, Quaresima, Silvia, Shalaby, Mostafa, Sileri, Pierpaolo   +7 more
core   +1 more source

Digital Anal Rectal Examination Usage Among Individuals at Increased Risk for Anal Cancer [PDF]

, 2023
Alan G. Nyitray, Timothy J. Ridolfi, Jenna Nitkowski, Timothy L. McAuliffe, Ashish A. Deshmukh, Anna R. Giuliano, Elizabeth Y. Chiao, The Prevent Anal Cancer Self-Swab Study Team   +7 more
openalex   +1 more source

First Successful Regeneration of a Structurally Native‐Like Colon Using a Bioabsorbable Polymer Sheet

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrated that a bioabsorbable polymer sheet (BAPS) can regenerate approximately half the circumference of the colon with native‐like structure and function in an experimental setting. As the model involved immediate closure after perforation and did not reproduce peritonitis, caution is required when considering clinical applicability ...
Junpei Takashima, Mitsuo Miyazawa, Masayasu Aikawa, Daisuke Fujimoto, Hirotoshi Kobayashi   +4 more
wiley   +1 more source

Awareness and knowledge of anal cancer in a community-recruited sample targeting people with HIV and gay/bisexual men

Papillomavirus Research, 2018
Background: Anal cancer disproportionately affects gay and bisexual men (GBM), especially those with HIV infection. We explored the awareness and understanding of human papillomavirus (HPV) and anal cancer in a community-based cohort, to inform future ...
Richard Hillman, Lance Feeney, Jeff Jin, Craig Cooper, David Templeton, Matt O’Dwyer, Mary Poynten   +6 more
doaj   +1 more source

Sexually transmitted infections (STI) in men who have sex with men (MSM) [PDF]

, 2009
The impact of increasingly efficient antiretroviral therapy (ART) on survival and general well-being has contributed to a "business as usual" attitude to sex among men who have sex with men (MSM).
Blaxhult, A., Bratt, G. A., Cullberg, M., Edlund, M., Eriksson, L. E., Hejdeman, B.   +5 more
core   +1 more source

Mature Tertiary Lymphoid Structures Indicate Good Chemotherapy Response and Prognosis in Advanced Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi, Chika Komine, Gendensuren Dorjkhorloo, Takuya Shiraishi, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Takehiko Yokobori, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Prevalence and Predictors of Sexual Dysfunction (SD) after Treatment of Localized Rectal and Anal Cancer (LRAC) [PDF]

, 2023
H.N. Yankey, María Dolores López, Karthik Devarajan, Ray E. Gleason, A.K. Pirlamarla, T. Dougherty, Efrat Dotan, Jeffrey M. Farma, N.E. Vijayvergia, Jennifer Barsky Reese, Joshua E. Meyer   +10 more
openalex   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source

A rare case of rectal cancer with perianal metastasis: a case report

World Journal of Surgical Oncology, 2019
Background Cancer metastasis from colon cancer to an anal fistula is very rare. We herein reported a rare case in which local excision was performed for metastatic anal fistula cancer originating from rectal cancer.
Takuto Ikeda, Atsushi Nanashima, Akiko Ichihara, Eiji Kitamura, Kenzo Nagatomo, Hiroyuki Tanaka   +5 more
doaj   +1 more source