Results 161 to 170 of about 625,843 (401)

THE EVALUATION OF ANALGESIC POTENCY OF DRUGS USING THERMAL STIMULATION IN THE RAT [PDF]

, 1952
H. Jackson
openalex   +1 more source

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression

Proceedings of the National Academy of Sciences of the United States of America, 2002
N. Chandrasekharan, H. Dai, K. Roos, N. Evanson, Joshua Tomsik, T. Elton, D. Simmons   +6 more
semanticscholar   +1 more source

Analgesics [PDF]

Postgraduate Medical Journal, 1984
openaire   +2 more sources

Analgesic nephropathy [PDF]

Nephrology Dialysis Transplantation, 1996
De Broe, M. E., Elseviers, M. M., Bengtsson, U., Mihatsch, M. J., Molzahn, M., Pommer, W., Ritz, E., Schwarz, A.   +7 more
openaire   +3 more sources

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Stereotypical escape behavior in Caenorhabditis elegans allows quantification of nociceptive stimuli levels

, 2016
Experiments of pain with human subjects are difficult, subjective, and ethically constrained. Since the molecular mechanisms of pain transduction are reasonably conserved among different species, these problems are partially solved by the use of animal ...
Leung, Kawai, Mohammadi, Aylia, Nemenman, Ilya, Ryu, William S.   +3 more
core   +2 more sources

ANIMAL EXPERIMENTATION IN STUDYING ADDICTION TO THE NEWER SYNTHETIC ANALGESICS [PDF]

, 1948
M.H. SEEVERS
openalex   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Effects of analgesic drugs in the mice repeatedly injected with histamine and histamine liberators

, 1959
Hiroyuki Ohno
openalex   +2 more sources