Results 171 to 180 of about 317,384 (310)
Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients
Annals of Neurology, EarlyView.Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer +14 more
wiley +1 more source
Analgesic and antiinflammatory effects of cucumis dipsaceus
, 1999 The pharmacological study showed high analgesic and antiinflammatory activities of the crude ethanolic extract and its petroleum eether, dichloromethane and methanolic fractions of the mature fruits of Cucumis dipsaceus.
Marín, Maria Teresa +3 more
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Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To compare postoperative complications, rehabilitation outcomes, and health care utilization in children undergoing primary medial patellofemoral ligament reconstruction for patellofemoral instability with and without a pre‐existing mental illness. Methods The TriNetX U.S.
Haad A. Arif +4 more
wiley +1 more source
Analgesic effects of calcitonin on radicular pain in male rats
, 2019 Yoshinori Terashima,1,2 Tsuneo Takebayashi,3 Shunsuke Jimbo,1 Izaya Ogon,1 Tatsuya Sato,2 Nobutoshi Ichise,2 Noritsugu Tohse,2 Toshihiko Yamashita1 1Department of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-0061 ...
Sato T +7 more
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Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To use a large, multi‐institutional database to characterize the outcomes and complication profile after primary acromioclavicular (AC) joint reconstruction and to evaluate potential sex‐related differences in outcomes and complications. Methods The TriNetX national database was queried for patients undergoing AC joint reconstruction between ...
Scott Fong +10 more
wiley +1 more source
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To identify risk factors that predict the need for rescue opioid use and patient‐reported outcomes following an opioid‐limiting postoperative analgesia protocol after anterior cruciate ligament reconstruction. Methods This prospective cohort study recruited 44 patients undergoing primary arthroscopic‐assisted anterior cruciate ligament ...
Eric V. Neufeld +6 more
wiley +1 more source
Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model
, 2018 Jared T Wilsey, Julie H Block Medtronic Spine Division, Memphis, TN, USA Background: Previous research suggests that the α2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on ...
Block JH, Wilsey JT
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Arthritis &Rheumatology, EarlyView.Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat +14 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco +8 more
wiley +1 more source