Results 161 to 170 of about 235,740 (266)

US multicentre randomised controlled trial protocol: Comparing Analgesic Regimen Effectiveness and Safety after surgery trial for Kids (CARES for Kids). [PDF]

BMJ Open
Lee JS, Bicket MC, Mansfield SA, Rabbitts JA, Van Horn A, Perrone EE, Chua KP, Voepel-Lewis T, Waljee J, Brummett C, Hutmacher C, Li Y, Kelley-Quon LI, CARES for Kids Investigators.   +13 more
europepmc   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

Herbal medicine as a complementary therapy for dysmenorrhea: effects on pain and reduction of analgesic use. [PDF]

Front Med (Lausanne)
Sung SH, Bae K, Jeong H, Kim DI, Park M.
europepmc   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Acupressure Needle Therapy Combined with Lumbar Plexus Block in Patients Undergoing Hip Arthroplasty. [PDF]

J Pain Res
Huang C, Zhou J, Liu H, Ju N, Yang P, Zhu S, Li J, Zhang X.   +7 more
europepmc   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian, Carlos Horacio Luna‐Flores, Xu Li, Sally L. Gras, Robert E. Speight   +4 more
wiley   +1 more source

How Can the Sedative and Analgesic Effects of Virtual Reality Technology Be More Precisely Assessed in Pediatric Dental Care? Methodological Insights from an Ongoing Randomized Controlled Trial [Letter]. [PDF]

J Pain Res
Zhao FY, Fu QQ, Zhu JY.
europepmc   +1 more source

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

BMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang, Lusen Shi, Xinhui Liu, Zhong Zhuang, Zhichao Feng, Chunhui Sun, Jingang Wang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shuping Wang, Hengxing Zhou, Na Ren   +11 more
wiley   +1 more source

Efficacy and Safety of Intrathecal Buprenorphine for Postoperative Analgesia in Cesarean Delivery: A Systematic Review of Randomized Controlled Trials. [PDF]

Cureus
Corriveau LG.
europepmc   +1 more source

Variations in Human Trigeminal and Facial Nerve Branches and Foramina Identified by Dissection and Microcomputed Tomography

Clinical Anatomy, EarlyView.
ABSTRACT The aim of this study was to identify branches of the trigeminal and facial nerves (FNs) relevant to surgical incisions and injections and the scalp block techniques in the frontotemporal region, and to determine their relationships with superficial vascular structures and bony landmarks.
Hannah L. Grimes, Valentina Pizzuti, Maria A. Wright, Kane P. J. Colston, Thomas Santarius, Susan Jones   +5 more
wiley   +1 more source