Results 161 to 170 of about 328,147 (311)

Animal models for investigating post‐stroke cognitive impairment: A neurovascular trafficking perspective

Animal Models and Experimental Medicine, EarlyView.
Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley   +1 more source

Analgesic Prescribing in Medically Complex Adult Outpatients Aged ≥40 Years: A Hierarchical Analysis of Comorbidity-Associated Patterns. [PDF]

J Clin Med
Alqurain AA, Alshammari A, Alhomoud F, Alhomoud FK, Alsalman AJ, Alshammari MK, Gharash HA, Alshawaf AJ.   +7 more
europepmc   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Analgesic headache [PDF]

BMJ, 1995
openaire   +2 more sources

Pain Management in Older Adults: An Interprofessional Training Approach Assessed by Script Concordance Tests. [PDF]

Pain Pract
Meurant A, Bonnet V, Gakuba C, Villain C, Loggia G.   +4 more
europepmc   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +1 more source

The Use of Unloader Bracing in the Management of Knee Osteoarthritis: A Modified Delphi Consensus Study

Arthroscopy, EarlyView.
Purpose To develop international expert consensus on the role of unloader bracing in the management of tibiofemoral osteoarthritis (OA) by addressing indications, contraindications, clinical evaluation, perioperative applications, and research priorities using a modified Delphi methodology.
Jonathan T. Super, Luke V. Tollefson, Iain R. Murray, Jorge Chahla, Andrew G. Geeslin, Darren L. Johnson, Ciara M. Stevenson, Robert F. LaPrade, Reykjavik Bracing Consensus Study Group, Robert F. LaPrade, Scott Anderson, Adam W. Anz, Sascha Beck, Andrew S. Bernhardson, Jorge Chahla, Anikar Chhabra, Mark E. Cinque, William M. Cregar, Pieter J. Emans, Scott C. Faucett, Andrew G. Geeslin, Darren L. Johnson, Tobias M. Jung, Patrick W. Kane, Nicholas I. Kennedy, Vickas Khanna, Cory A. Kwong, Christopher M. LaPrade, Martin Lind, Parth Lodhia, Gilbert Moatshe, Iain R. Murray, Johnathan Riboh, Anders Stalman, Ciara M. Stevenson, Wybren A. Van Der Wal, David Wasserstein, Daniel B. Whelan   +37 more
wiley   +1 more source

Analgesic Efficacy of Ropivacaine-P407 Gel vs. Bupivacaine in Single-Port-Assisted Hysterectomy: A Propensity Score-Matched Analysis. [PDF]

Yonsei Med J
Kim JC, Lee YJ, Nam EJ, Kim S, Lee JY, Kim YT, Kim SW.   +6 more
europepmc   +1 more source

Unloader Bracing Is a Biomechanically Rational and Clinically Useful Intervention in Selected Patients With Tibiofemoral Joint Cartilage Pathology: A Modified Delphi Consensus Study

Arthroscopy, EarlyView.
Purpose To establish an international expert consensus on the role of unloader bracing in the management of focal tibiofemoral cartilage lesions using Delphi methodology to inform clinical decision‐making in both nonoperative and operative contexts and identify future research priorities.
Jonathan T. Super, Luke V. Tollefson, Iain R. Murray, Jorge Chahla, Andrew G. Geeslin, Darren L. Johnson, Ciara M. Stevenson, Robert F. LaPrade, Reykjavik Bracing Consensus Study Group, Robert. F. LaPrade, Scott Anderson, Adam. W. Anz, Sascha Beck, Andrew S. Bernhardson, Jorge Chahla, Anikar Chhabra, Mark E. Cinque, William M. Cregar, Pieter J. Emans, Scott C. Faucett, Andrew G. Geeslin, Darren L. Johnson, Tobias. M. Jung, Patrick. W. Kane, Nicholas I. Kennedy, Vickas Khanna, Cory A. Kwong, Christopher M. LaPrade, Martin Lind, Parth. Lodhia, Gilbert Moatshe, Iain R. Murray, Johnathan Riboh, Anders Stalman, Ciara. M. Stevenson, Wybren A. Van Der Wal, David Wasserstein, Daniel B. Whelan   +37 more
wiley   +1 more source