Results 181 to 190 of about 317,384 (310)

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang   +5 more
wiley   +1 more source

Modified Das De Procedure in Peroneus Longus Tendon Dislocation: Technical Note

open access: yesArthroscopy Techniques, EarlyView.
Abstract Peroneal tendon dislocation is an uncommon ankle injury that may be misinterpreted as a lateral ankle sprain due to similar clinical characteristics. It frequently leads to delayed treatment and recurrent instability. Although various surgical approaches have been described, including osseous procedures such as groove deepening and soft‐tissue
I. Wayan Subawa, Febyan Febyan
wiley   +1 more source

Arthroscopic Technique for Posterior Labral Repair in the Beach‐Chair Position

open access: yesArthroscopy Techniques, EarlyView.
Abstract Posterior labral repair is commonly performed in the lateral decubitus position; however, comparable outcomes have been reported using the beach‐chair position. Limited visualization of the posterior‐inferior glenoid remains a perceived disadvantage of the beach‐chair setup.
Saad M. AlQahtani   +2 more
wiley   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

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