Results 201 to 210 of about 235,740 (266)

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Collision Sports: The Need for Further Education in Rugby. [PDF]

Cureus
Papadimos TJ, Altenhof B, Uberoi R, Reinert JP.   +3 more
europepmc   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh, Kazushi Aoto, Atsuo Fukuda, Hirotomo Saitsu   +3 more
wiley   +1 more source

Pain and Prose: Tracing the Opioid Epidemic in Stephen King's Novels. [PDF]

Nordisk Alkohol Nark
Marquez-Romero JM.
europepmc   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

Epilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden, Verena Buchecker, Amelie Wagner, Victoria M. Stocker, Liga Zvejniece, Heidrun Potschka   +5 more
wiley   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil, Margaret M. Donahue, Cathy B. Dang, Gergely Tarcsay, Laura A. Ewell   +4 more
wiley   +1 more source

Comparison of the Effects of Intraoperative Dexmedetomidine and Fentanyl Infusion on Postoperative Agitation and Analgesia in Pediatric Patients Undergoing Tonsillectomy and Adenoidectomy: A Prospective Randomized Trial. [PDF]

Children (Basel)
Gul YG, Yildiz S, Güngör H, Omur B, Karaaslan P, Ciftci B.   +5 more
europepmc   +1 more source

SPINAL: study protocol for a multicenter non-inferiority trial evaluating reduce vertebral irradiation volumes in palliative radiotherapy for spinal bone metastases on analgesic efficacy. [PDF]

BMC Cancer
Faivre JC, Lambert A, Bruand M, Francais A, Supiot S, Thureau S, Bourbonne V, Tomaszewski F, Charra-Brunaud C, Py JF, Stefani A, Jolnerovski M, Demogeot N, Cuenin M, Renard S, Sellami S, Trampetti I, Bernier-Chastagner V, Jacques J, Agnoux E, Appavou RA, Gehin W, Martz N, Mammari N.   +23 more
europepmc   +1 more source

Optimizing Post-operative Pain Management in Knee Arthroscopy: A Double-Blinded Randomized Controlled Trial of Regional Anesthesia with and without Local Infiltration. [PDF]

J Orthop Case Rep
Vuthpala VM, Ilinani PKR, Sankineani SR, Kidiyoor B, Quadri SY, Chirra CR.   +5 more
europepmc   +1 more source

Synaptic Plasticity as a Mechanism of Opioid Tolerance and Hyperalgesia. [PDF]

Biology (Basel)
Qin F, Wang Q, Abdi S, Li L.
europepmc   +1 more source