Results 191 to 200 of about 317,384 (310)

International variability in pain management for the minimally invasive repair of pectus excavatum: a survey by the Chest Wall International Group. [PDF]

J Thorac Dis
van Polen EJ, Daemen JHT, Knol D, van Roozendaal LM, Franssen AJPM, Janssen N, Jaroszewski D, McMahon LE, Martinez-Ferro M, de Campos JRM, López M, Vissers YLJ, de Loos ER, CWIG collaborator group.   +13 more
europepmc   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Paediatric regional anaesthesia and peripheral nerve blocks in paediatric outpatient surgery. Prospective, single-center, pragmatic comparative cohort study. [PDF]

Pediatr Surg Int
Perez D, Jaber G, Neeman BB, Raisin G, Zeldin A, Armon Y, Feldman E, Gozal Y, Ostrovsky IA, Chertin B.   +9 more
europepmc   +1 more source

Adjunctive analgesic therapy

Adjuvant analgesics are drugs that have weak or nonexistent analgesic action when administered alone but can enhance analgesic actions when coadministered with known analgesic agents. Such agents are often administered in cases of refractory pain.

core  

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Oxycodone vs Remifentanil for Analgesia in Mechanically Ventilated ICU Patients: Retrospective Review of Medical Records for Delirium Incidence and Duration. [PDF]

J Pain Res
Liu S, Wei Y, Jin J, Guo Y, Fan Z, Kong J.   +5 more
europepmc   +1 more source

Analgesic nephropathy [PDF]

Journal of Clinical Pathology, 1975
openaire   +3 more sources

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Analgesic Efficacy of Continuous Bupivacaine Infusion versus Liposomal Bupivacaine in Parasacral Ischial Plane Block After Total Knee Arthroplasty: An Open-Label, Randomized, Controlled, Non-Inferiority Study. [PDF]

Drug Des Devel Ther
Pan X, Ye P, Xie Y, Chen Y, Fan H, Huang Y, Zheng C, Zheng X, Zheng T.   +8 more
europepmc   +1 more source