Results 81 to 90 of about 435,526 (355)

Dexmedetomidine: present and future directions [PDF]

Korean Journal of Anesthesiology, 2019
Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
doaj   +1 more source

In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]

, 2018
Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta, Negri, Lucia, Rief, Silvia, Schmidhammer, Helmut, Spetea, Mariana.   +4 more
core   +2 more sources

The Analgesic Antipyretics [PDF]

The American Journal of the Medical Sciences, 1902
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openaire   +2 more sources

Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

Arthritis Care &Research, EarlyView.
Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson, Mari Imamura, Clare Robertson, Daniel Whibley, Lorna Aucott, Katie Gillies, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole K. Y. Tang, Gary J. Macfarlane, Miriam Brazzelli   +11 more
wiley   +1 more source

Intraoperative Ketamine and Magnesium Therapy to Control Postoperative Pain After Abdominoplasty and/or Liposuction: A Clinical Randomized Trial

Journal of Pain Research, 2020
Verónica Varas,1 Paz Bertinelli,1 Pablo Carrasco,1 Nicole Souper,1 Patricio Álvarez,1 Stefan Danilla,2 José Ignacio Egaña,1,3 Antonello Penna,1,4 Sergio Sepúlveda,2 Virginia Arancibia,1 María Gabriela Á ...
Varas V, Bertinelli P, Carrasco P, Souper N, Álvarez P, Danilla S, Egaña JI, Penna A, Sepúlveda S, Arancibia V, Álvarez MG, Vergara R   +11 more
doaj  

Antinociceptive and Anti-Inflammatory Effects of Geum iranicum Khatamsaz Methanol Extract in Mice [PDF]

Research Journal of Pharmacognosy, 2019
Background and objectives:Traditionally, Geum species from Rosaceae family have been used for treating inflammatory disorders. Geum iranicum Khatamsaz is endemic to Iran.
Nematollah Ahangar, Fatemeh Mirzaee, Maryam Feizbakhsh, Sara Pirhayati, Somayeh Shahani*   +4 more
doaj   +1 more source

Dexmedetomidine decreases stress post-operative in pediatrics

Egyptian Journal of Anaesthesia, 2022
Introduction Tracheal extubation causes hypertension and tachycardia. These associated hemodynamic changes are due to sympathetic discharge due to epipharyngeal and laryngeal stimulation.(1)Aim of work Dexmedetomidine is an effective sedative and ...
Taha Magdy AllamFarrag, Mai Abd El Fattah Ahmed Madkour, AbdelhayAbdelgayed Abdelhay Ebade, Victor Farouk JaccoubMetry   +3 more
doaj   +1 more source

Patient and clinician factors associated with prehospital pain treatment and outcomes: cross sectional study [PDF]

, 2018
Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.Objective: We aimed to identify how patient (age, sex, condition) and paramedic factors (sex, role) affected prehospital analgesic administration and pain alleviation.
,, Asghar, Zahid, Foster, Theresa, Lord, Bill, Phung, Viet-Hai, Pocock, Helen, Siriwardena, A. Niroshan, Snooks, Helen, Williams, Julia   +8 more
core   +3 more sources

Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics

Journal of Neuroscience, 2015
Treating pain is one of the most difficult challenges in medicine and a key facet of disease management. The isolation of morphine by Friedrich Sertürner in 1804 added an essential pharmacological tool in the treatment of pain and spawned the discovery ...
Tuan Trang, R. Al-Hasani, D. Salvemini, M. Salter, H. Gutstein, C. Cahill   +5 more
semanticscholar   +1 more source

Sequence Analysis to Phenotype Healthcare Patterns in Adults with Musculoskeletal Conditions Using Primary Care Electronic Health Records

Arthritis Care &Research, Accepted Article.
Objective The aim of this study was to apply sequence analysis (SA) to phenotype healthcare patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these healthcare patterns and post‐consultation patient's self‐reported outcome.
Smitha Mathew, George Peat, Emma Parry, Ross Wilkie, Kelvin P Jordan, Jonathan C Hill, Dahai Yu   +6 more
wiley   +1 more source