Results 71 to 80 of about 167,491,685 (275)
Optimization of Axial Misalignment due to Glass Drilling by Statistical Methods
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020 Flat glass has a significant utilization in the domestic appliances sector. Drilling of glass is frequently used in the white goods sector. In this research, the glass drilling method is explained in detail, the determined axial misalignment values using
Sabri Ozturk, Faruk Harmancı
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Results of fully crossed analysis of variance (ANOVA).
, 2018 Results of fully crossed analysis of variance (ANOVA).
Lawrence E. Reeves (4775199) +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Objective evaluation of precision requirements for geochemical analysis using robust analysis of variance [PDF]
, 1992 The pursuit of high precision in geochemical analysis has no inherent limit. An appropriate analytical precision requirement can be set, however, by comparing the “analytical variance” with the other sources of variance in geochemical data.The purpose of
Ramsey, M.H., Thompson, M., Hale, M.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Antioxidants, 2019 Resveratrol is an antioxidant abundant in red fruits, and one of the most powerful inhibiting reactive oxygen species (ROS) and oxidative stress (OS) produced by human metabolism.
César Leyva-Porras +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Resolution of Students t-tests, ANOVA and analysis of variance components from intermediary data [PDF]
, 2017 Significance testing in comparisons is based on Student’s t-tests for pairs and analysis of variance (ANOVA) for simultaneous comparison of several procedures.
Anders Kallner +2 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source