Results 71 to 80 of about 174,852,288 (260)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Analysis of variance (ANOVA) for response surface quadratic model.

, 2019
Analysis of variance (ANOVA) for response surface quadratic model.
Yen-Tso Lai (6335372), Chia-Nuan Lai (6335375), Kuan-Chen Cheng (2159011), Ying-Jang Lai (511371)   +3 more
core   +1 more source

Optimizing 3D printing parameters for PLA and PETG: advancing high-quality skull implant production [PDF]

Engineering and Technology Journal
This study investigates the mechanical performance of 3D-printed polylactic acid and polyethylene terephthalate glycol materials by examining the effects of three crucial printing parameters (layer thickness, infill density, and infill pattern).
Reem Khzzal, Marwan Nafaa, Wisam Hamdan
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Kinematic parameters used for the analysis of variance (ANOVA).

, 2016
Kinematic parameters used for the analysis of variance (ANOVA).
Paul Filipetti (2822006), Elisabeth Kolanowski (2822009), Frédéric Chantraine (178216), Angélique Remacle (2822003), Céline Schreiber (2822012), Florent Moissenet (2822000)   +5 more
core   +1 more source

Analysis of variance (ANOVA) among 72 teff samples from three among three administrative zones.

, 2022
Analysis of variance (ANOVA) among 72 teff samples from three among three administrative zones.
Minaleshewa Atlabachew (4519726), Marie Yayinie (13190023), Tihitinna Asmellash (13190017), Woldegiorgis Hilluf (13190020), Tessera Alemneh Wubieneh (13190026), Chaltu Reta (13190014)   +5 more
core   +1 more source

Optimized biosorption of Cd (II) ions using activated

Next Sustainability
The release of cadmium metal into the environment is sufficient to severely degrade the ecological health. The biosorptive potential of activated Araucaria heterophylla (AHL) leaves for Cd (II) ion removal from synthetic wastewater was studied ...
Madhumita Bisht, Hemant Kumar Joshi, Mahesh Chandra Vishwakarma, Dinesh Chandra Joshi, Megha Budakoti, Rajesh Kumar, Ankita Negi, Himani Joshi, Neeraj Ram, Arpit Kumar Joshi, Deepika Arya, Dheeraj Kumar Dubey, Sushil Kumar Joshi, Narendra Singh Bhandari   +13 more
doaj   +1 more source

Optimization of Axial Misalignment due to Glass Drilling by Statistical Methods

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
Flat glass has a significant utilization in the domestic appliances sector. Drilling of glass is frequently used in the white goods sector. In this research, the glass drilling method is explained in detail, the determined axial misalignment values using
Sabri Ozturk, Faruk Harmancı
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source